Evidence map›Paper›PMID 32139013›Full record

ReviewBest practice & research. Clinical haematology2020

Current and potential applications of positron emission tomography for multiple myeloma and plasma cell disorders.

Gary A Ulaner, C Ola Landgren

Open access · greenAbstract readReview
In one paragraph

Review in Best practice & research. Clinical haematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. ACS omega · 2023
    Article
  5. Review
  6. European journal of nuclear medicine and molecular imaging · 2022
    Article
  7. The "Undetermined Significance" ofMedicina (Kaunas, Lithuania) · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gary A UlanerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA; Weill Cornell Medical College, New York, NY, 10065, USA. Electronic address: ulanerg@mskcc.org.
C Ola LandgrenDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA; Weill Cornell Medical College, New York, NY, 10065, USA. Electronic address: landgrec@mskcc.org.
Cornell University · USMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Fluorine-18 (18F)-fluorodeoxyglucose (FDG) positron emission tomography (PET) allows evaluation of elevated glucose metabolism in malignancies. There has been increasing interest in FDG PET/CT for plasma cell disorders since the International Myeloma Working Group outlined multiple applications of this imaging modality, including distinguishing smoldering myeloma from active multiple myeloma, confirmation of solitary plasmacytoma, and multiple indications in patients with known multiple myeloma, including determining extent of initial disease, monitoring therapy response, and detection of residual disease following therapy. The field of molecular imaging is now shifting focus from evaluation of metabolism to targeted evaluation of specific tumor markers. Targeted PET imaging targeted of CXCR4 and CD38 has advanced into translational clinical trials, bringing us closer to powerful imaging options for myeloma. In this review we discuss the current applications of FDG PET/CT in plasma cell disorders, as well as advances in targeted PET imaging.

Indexed as

ADP-ribosyl Cyclase 1B-Cell Maturation AntigenBiomarkers, TumorBone MarrowDisease ProgressionFluorodeoxyglucose F18Gene ExpressionHumansMembrane GlycoproteinsNeoplasm ProteinsNeoplasm, ResidualPlasma CellsPlasmacytomaPositron Emission Tomography Computed TomographyRadiopharmaceuticalsReceptors, CXCR4ADP-ribosyl Cyclase 1B-Cell Maturation AntigenBiomarkers, TumorCD38 protein, humanCXCR4 protein, humanFluorodeoxyglucose F18Membrane GlycoproteinsNeoplasm ProteinsRadiopharmaceuticalsReceptors, CXCR4TNFRSF17 protein, human18F-fluorodeoxyglucose (FDG)immunoPETMultiple myelomaPositron emission tomography (PET)

Identifiers

PMID32139013
PMCPMC7410322
OpenAlexW2999151051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.