Evidence map›Paper›PMID 32138936›Full record

ArticleBehavior therapy2020

Children's Facial Muscular Movements and Risk for Early Psychopathology: Assessing Clinical Utility.

Adam S Grabell, Hannah M Jones, Aimee E Wilett, Lisa M Bemis, Lauren S Wakschlag, Susan B Perlman

Open access · greenAbstract read
In one paragraph

Article in Behavior therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. A network approach to the investigation of childhood irritability: probing frustration using social stimuli.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Adam S GrabellUniversity of Massachusetts, Amherst. Electronic address: agrabell@umass.edu.
Hannah M JonesUniversity of Pittsburgh School of Medicine.
Aimee E WilettUniversity of Pittsburgh School of Medicine.
Lisa M BemisUniversity of Pittsburgh School of Medicine.
Lauren S WakschlagNorthwestern University Feinberg School of Medicine.
Susan B PerlmanWashington University School of Medicine in St. Louis.
University of Pittsburgh · USUniversity of Massachusetts Amherst · USWashington University in St. Louis · US

Funding

Generating an Earlier Science of When to Worry: A Neurodevelopmental, Transactional Approach to Characterizing Irritability Patterns Beginning in InfancyR01MH107652 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WAKSCHLAG, LAUREN S · 2016 to 2021
$4.0M
From Irritability to Impairment: How Neurodevelopment of Executive Function and Parent-Child Neural Synchrony Influence the Transition from Normal to Abnormal FunctioningR01MH107540 · NIMH · WASHINGTON UNIVERSITY · PI PERLMAN, SUSAN B · 2015 to 2019
$3.1M
Neural and behavioral correlates of deliberate emotion regulation in early childhood: testing unique links to emerging irritability.K23MH111708 · NIMH · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GRABELL, ADAM · 2017 to 2022
$945k
Neural Mechanisms for Early Development of Pervasive Anger and IrritabilityK01MH094467 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PERLMAN, SUSAN B · 2011 to 2014
$616k
A Study of Preschool Irritability: Brain Imaging in the Clinic SettingR21MH100189 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PERLMAN, SUSAN B · 2014 to 2015
$407k
NIMH NIH HHS K01 MH094467NIMH NIH HHS K23 MH111708NIMH NIH HHS R01 MH107540NIMH NIH HHS R01 MH107652NIMH NIH HHS R21 MH100189
6 · The paper itself

Abstract

Standardized developmentally based assessment systems have transformed the capacity to identify transdiagnostic behavioral markers of mental disorder risk in early childhood, notably, clinically significant irritability and externalizing behaviors. However, behavior-based instruments that both differentiate risk for persistent psychopathology from normative misbehavior, and are feasible for community clinicians to implement, are in nascent phases of development. Young children's facial expressions during frustration challenges may form the basis for novel assessments tools that are flexible, quick, and easy to implement as markers of psychopathology to complement validated questionnaires. However, the accuracy of facial expressions to correctly classify young children falling above and below clinical cut-offs is unknown. Our goal was to test how facial expressions during frustration, defined by different facial muscular movements, related to individual differences in irritability and externalizing behaviors and discriminated children with clinically significant levels from peers. Participants were 79 children (ages 3-7) who completed a short, moderately frustrating computer task while facial expressions were recorded. Only negative facial expressions that included eye constriction related to irritability and externalizing behaviors and were clinically discriminating. Moreover, these expressions significantly discriminated children with and without clinically significant irritability and externalizing symptoms with high Area Under the Curve (AUC) values (> .75) indicating good clinical utility. In contrast, expressions without eye constriction showed no clinical utility. The presence of negative expressions with eye constriction in response to a short frustration prompt may serve as an indicator of early psychopathology, raising the potential for novel assessment tools that may enhance precision of early identification.

Indexed as

Facial ExpressionChildChild, PreschoolFacial MusclesFemaleFrustrationHumansIrritable MoodMaleMental DisordersProblem Behaviorchildfacial expressionpsychopathologyrisk assessmentROC curve

Identifiers

PMID32138936
PMCPMC7476425
OpenAlexW2967740798

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.