ArticleBMC pregnancy and childbirth2020
The association between symptoms of depression during pregnancy and low birth weight: a prospective study.
Article in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Depression and antidepressant use in pregnancy and adverse maternal and offspring outcomes: a systematic review and meta-analysis.Molecular psychiatry · 2025Pooled it
- Pooled it
- Associations between intimate partner violence and adverse birth outcomes during pregnancy: a systematic review and meta-analysis.Frontiers in medicine · 2023Pooled it
- Perceived stress during labor and its association with depressive symptomatology, anxiety, and pain catastrophizing.Scientific reports · 2021Trial
- Time series analysis of anxiety and depression during pregnancy to postpartum depression based on cross-lagged model.World journal of psychiatry · 2026Article
- Placental and fetal consequences of maternal selective serotonin reuptake inhibitor use: current evidence and unresolved questions.Frontiers in pharmacology · 2026Review
- Longitudinal associations between maternal sleep, anxiety, depression across pregnancy trimesters and adverse pregnancy outcomes: a prospective cohort study.Reproductive health · 2025Article
- Birth Outcomes in the Hispanic Population in the United States: Trends, Variation, and Determinants (2011-2021).International journal of environmental research and public health · 2025Article
- Perinatal depressive and anxiety symptoms are associated with gut microbiota in pregnant women with overweight and obesity.Brain, behavior, & immunity - health · 2025Article
- Examining the role of socioeconomic adversity on depressive symptoms during pregnancy among non-Hispanic Black women.SSM. Mental health · 2025Article
- Predicting peripartum depression using elastic net regression and machine learning: the role of remnant cholesterol.BMC pregnancy and childbirth · 2025Article
- Association Between the Dietary Inflammatory Index and Depression in Mid-Pregnancy: Mediating Effect of Sleep Quality.Nutrients · 2025Article
- E-Screening for Prenatal Depression in Kampala, Uganda Using the Edinburgh Postnatal Depression Scale: Survey Results.Online journal of public health informatics · 2025Article
- Impact of prenatal depression, anxiety and stress on low birth weight: a retrospective case-control study in Karachi, Pakistan.BMJ public health · 2025Article
- Flooding and elevated prenatal depression in rural Bangladesh: A mixed methods study.PLOS global public health · 2025Article
- Association of Pregnant Women's Perinatal Depression with Sociodemographic, Anthropometric and Lifestyle Factors and Perinatal and Postnatal Outcomes: A Cross-Sectional Study.Journal of clinical medicine · 2024Article
- Concerns, Worries, and Fears During Pregnancy in Active-Duty United States Air Force Families.The Journal of perinatal education · 2024Article
- Factors associated with antenatal depression among women attending antenatal care at Mubende Regional Referral Hospital: a cross-sectional study.BMC women's health · 2024Article
- Maternal Antibiotic Exposure and the Risk of Developing Antenatal Depressive Symptoms.Journal of clinical medicine · 2024Article
- The impact of prenatal mental health on birth outcomes before and during the COVID-19 pandemic in Anhui, China.PloS one · 2024Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMost studies have showed that maternal depression is associated with pregnancy complications. However, there were limited evidences in Chinese population. We examined the associations of antenatal depression symptoms with pregnancy outcomes, especially for low birth weight.
methodsA total of 1377 singleton pregnant women were recruited from Nanshan Maternity & Child Healthcare Hospital of Shenzhen in this prospective cohort study. Depression symptoms were assessed by the Edinburgh postnatal depression scale (EPDS) questionnaire in the second trimester of gestation; cut-points for the indication of antenatal depression were ≧12 scores in this study. Socio-demographic data, life-style and pregnancy outcomes were collected through Shenzhen Maternity & Child Healthcare database. The risks of adverse outcomes in pregnant women with antenatal depression were determined by multivariate logistic regression and represented as odds ratio(OR) and 95% confidence interval (CI).
resultsOf the 1377 subjects, the prevalence of antenatal depression was 19.1%. The EPDS scores were 13.8 ± 2.0 and 6.5 ± 2.9 (P < 0.001) in subjects with and without antenatal depression, respectively. After adjustment for maternal age, education, parity, pre-pregnancy body mass index (BMI), residential area, fetal gender, an EPDS score ≥ 12 (versus. < 12) was associated with an increased risk for low birth weight (odds ratio: 2.05, 95% CI: 1.12-4.64), but not for preterm birth, large for gestational age, small for gestational age or macrosomia.
conclusionPregnant women presenting antenatal depressive symptoms are at elevated risk of low birth weight. Mental health problems of pregnancy should be addressed for the prevention of low birth weight.
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