Evidence map›Paper›PMID 32138353›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Novel Assessment of Urinary Albumin Excretion in Type 2 Diabetes Patients by Raman Spectroscopy.

Jose L Flores-Guerrero, Aaron Muñoz-Morales, Freddy Narea-Jimenez, Ricardo Perez-Fuentes, Enrique Torres-Rasgado, Guadalupe Ruiz-Vivanco, Naara Gonzalez-Viveros, Jorge Castro-Ramos

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  5. Applications and prospects of biomaterials in diabetes management.Frontiers in bioengineering and biotechnology · 2025
    Review
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Jose L Flores-GuerreroDepartment of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Aaron Muñoz-MoralesDepartment of Physics, Faculty of Experimental Sciences and Technology, Center of Medical and Biotechnology Research, University of Carabobo, Valencia 2005, Venezuela.
Freddy Narea-JimenezOptics coordination, Biomedical Optics Group, National Institute of Astrophysics, Optics and Electronics, INAOE, Puebla 72840, Mexico.
Ricardo Perez-FuentesDepartment of Chronic Disease Physiopathology, East Center of Biomedical Research, Mexican Social Security Institute, CIBIOR, Puebla 74360, Mexico.
Enrique Torres-RasgadoFaculty of Medicine, Meritorious Autonomous University of Puebla, BUAP, Puebla 72589, Mexico.
Guadalupe Ruiz-VivancoDepartment of Chronic Disease Physiopathology, East Center of Biomedical Research, Mexican Social Security Institute, CIBIOR, Puebla 74360, Mexico.
Naara Gonzalez-ViverosOptics coordination, Biomedical Optics Group, National Institute of Astrophysics, Optics and Electronics, INAOE, Puebla 72840, Mexico.
Jorge Castro-RamosOptics coordination, Biomedical Optics Group, National Institute of Astrophysics, Optics and Electronics, INAOE, Puebla 72840, Mexico.
National Institute of Astrophysics, Optics and Electronics · MXMexican Social Security Institute · MXBenemérita Universidad Autónoma de Puebla · MXUniversity Medical Center Groningen · NLUniversity of Carabobo · VE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

. Urinary albumin excretion remains the key biomarker to detect renal complications in type 2 diabetes. As diabetes epidemy increases, particularly in low-income countries, efficient and low-cost methods to measure urinary albumin are needed. In this pilot study, we evaluated the performance of Raman spectroscopy in the assessment of urinary albumin in patients with type 2 diabetes. The spectral Raman analysis of albumin was performed using artificial urine, at five concentrations of albumin and 24 h collection urine samples from ten patients with Type 2 Diabetes. The spectra were obtained after removing the background fluorescence and fitting Gaussian curves to spectral regions containing features of such metabolites. In the samples from patients with type 2 diabetes, we identified the presence of albumin in the peaks of the spectrum located at 663.07, 993.43, 1021.43, 1235.28, 1429.91 and 1633.91 cm

Indexed as

albumindiabetic nephropathykidney diseaseRaman spectroscopytype 2 diabetes

Identifiers

PMID32138353
PMCPMC7151048
OpenAlexW3009865587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.