Evidence map›Paper›PMID 32138329›Full record

ReviewMolecules (Basel, Switzerland)2020

A Supramolecular Approach to Structure-Based Design with A Focus on Synthons Hierarchy in Ornithine-Derived Ligands: Review, Synthesis, Experimental and in Silico Studies.

Joanna Bojarska, Milan Remko, Martin Breza, Izabela D Madura, Krzysztof Kaczmarek, Janusz Zabrocki, Wojciech M Wolf

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
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  11. Article
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  14. Heliyon · 2024
    Article
  15. Unveiling the Potential ofPharmaceuticals (Basel, Switzerland) · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Assessment of the Antioxidant and Antimicrobial Potential ofAntibiotics (Basel, Switzerland) · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joanna BojarskaInstitute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.
Milan RemkoRemedika, Sustekova, 1 85104 Bratislava, Slovakia.
Martin BrezaDepartment of Physical Chemistry, Slovak Technical University, Radlinskeho 9, SK-81237 Bratislava, Slovakia.
Izabela D MaduraWarsaw University of Technology, Faculty of Chemistry, Noakowskiego, 3 00-664 Warszawa, Poland.
Krzysztof KaczmarekInstitute of Organic Chemistry, Lodz University of Technology, Faculty of Chemistry, Żeromskiego 116, 90-924 Lodz, Poland.
Janusz ZabrockiInstitute of Organic Chemistry, Lodz University of Technology, Faculty of Chemistry, Żeromskiego 116, 90-924 Lodz, Poland.
Wojciech M WolfInstitute of General and Ecological Chemistry, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116, 90-924 Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of living systems is controlled by non-covalent interactions to a very large extent. The latter are prone to extensive cooperation and like a virtuoso play a symphony of life

Indexed as

Databases, FactualHydrogen BondingMolecular ConformationMolecular StructureOrnithineOrnithineC-H…πC=O (lone pair)…π and N-O…π interactionsDFTdrug-likenesselectrostatic molecular potentialH-bond energiesmolecular (Hirshfeld) surfaceornithineProTox II.supramolecular synthonSwissADMEπ…π

Identifiers

PMID32138329
PMCPMC7179192

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.