Evidence map›Paper›PMID 32138326›Full record

ArticleInternational journal of molecular sciences2020

Tuberous Sclerosis Complex Axis Controls Renal Extracellular Vesicle Production and Protein Content.

Fahad Zadjali, Prashant Kumar, Ying Yao, Daniel Johnson, Aristotelis Astrinidis, Peter Vogel, Kenneth W Gross, John J Bissler

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Role of Extracellular Vesicles in TSC Renal Cystogenesis.International journal of molecular sciences · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Genes & diseases · 2022
    Article
  11. Racial Health Disparity and COVID-19.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Review
  12. Renal cystic disease in tuberous sclerosis complex.Experimental biology and medicine (Maywood, N.J.) · 2021
    Review
  13. Frontiers in physiology · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Fahad ZadjaliDepartment of Clinical Biochemistry, College of Medicine & Health Sciences, Muscat 123, Oman.ORCID 0000-0001-5891-4700
Prashant KumarDepartment of Pediatrics, University of Tennessee Health Science Center and Le Bonheur Children's Hospital, Memphis, TN 38103, USA.
Ying YaoDepartment of Pediatrics, University of Tennessee Health Science Center and Le Bonheur Children's Hospital, Memphis, TN 38103, USA.
Daniel JohnsonMolecular Bioinformatics Center, University of Tennessee Health Science Center Memphis, TN 38103, USA.
Aristotelis AstrinidisDepartment of Pediatrics, University of Tennessee Health Science Center and Le Bonheur Children's Hospital, Memphis, TN 38103, USA.
Peter VogelDepartment of Veterinary Pathology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.
Kenneth W GrossDepartment of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
John J BisslerDepartment of Pediatrics, University of Tennessee Health Science Center and Le Bonheur Children's Hospital, Memphis, TN 38103, USA.
University of Tennessee Health Science Center · USSt. Jude Children's Research Hospital · USRoswell Park Comprehensive Cancer Center · US

Funding

U.S. Department of Defense W81XWH-14-1-0343
6 · The paper itself

Abstract

The tuberous sclerosis complex (Tsc) proteins regulate the conserved mTORC1 growth regulation pathway. We identified that loss of the

Indexed as

AnimalsBlotting, WesternCell LineChromatography, GelExtracellular VesiclesKidneyMechanistic Target of Rapamycin Complex 1MiceProtein BindingProteomicsTetraspanin 28Tetraspanin 29Tetraspanin 30Tuberous SclerosisMechanistic Target of Rapamycin Complex 1Tetraspanin 28Tetraspanin 29Tetraspanin 30TSC complex, extracellular vesicles (EVs), mTORC1, renal cyst

Identifiers

PMID32138326
PMCPMC7084746
OpenAlexW3009766150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.