Evidence map›Paper›PMID 32138203›Full record

ArticlePolymers2020

Development and Characterization of Hemicellulose-Based Films for Antibacterial Wound-Dressing Application.

Naveed Ahmad, Danial Tayyeb, Imran Ali, Nabil K Alruwaili, Waqas Ahmad, Atta Ur Rehman, Abdul Haleem Khan, Mohammad Saeed Iqbal

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 72 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Naveed AhmadDepartment of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Aljouf 72388, Saudi Arabia.ORCID 0000-0003-2312-3137
Danial TayyebDepartment of Chemistry, Forman Christian College, Ferozepur Road, Lahore 54600, Pakista.
Imran AliDepartment of Chemistry, Forman Christian College, Ferozepur Road, Lahore 54600, Pakista.
Nabil K AlruwailiDepartment of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Aljouf 72388, Saudi Arabia.
Waqas AhmadSchool of Pharmaceutical Sciences, University of Science Malaysia, Pulau Pinang 11800, Malaysia.
Atta Ur RehmanDepartment of Pharmacy, Forman Christian College, Ferozepur Road, Lahore 54600, Pakistan.ORCID 0000-0001-8818-8754
Abdul Haleem KhanDepartment of Pharmacy, Forman Christian College, Ferozepur Road, Lahore 54600, Pakistan.
Mohammad Saeed IqbalDepartment of Chemistry, Forman Christian College, Ferozepur Road, Lahore 54600, Pakista.ORCID 0000-0002-2933-195X
Forman Christian College · PKJouf University · SAUniversiti Sains Malaysia · MY

Funding

Higher Education Commision, Pakistan Project # 21- 956/SRGP/R&D/HEC/2016
6 · The paper itself

Abstract

Hemicelluloses are biopolymers with versatile properties for biomedical applications. Herein, hemicellulose (arabinoxylan)-based antibacterial film dressings were prepared and characterized. Arabinoxylan was isolated from psyllium husk. Blank and gentamicin-loaded films were prepared by the solvent cast method using glycerol as the plasticizer. The appropriate composition of the films was obtained by varying the amounts of arabinoxylan, glycerol, and gentamicin. The films were found to be transparent, smooth, bubble-free, flexible, and easily peelable with 2% to 3% arabinoxylan. They had uniform thickness and swelled up to 60% of their initial size. The mechanical properties and water vapor transmission rate through the films were found to be suitable for wound-dressing application. Fourier transform infrared spectroscopy (FTIR) analysis confirmed drug-film compatibility. In an in vitro release study, more than 85% of the gentamicin was released from the films in 12 h. The antibacterial activities of the gentamicin-loaded films were found to be close to the standard gentamicin solution. The films were found to be cytocompatible in cell viability assay. These results suggested that hemicellulose-based films are promising materials for the dressing of infected wounds.

Indexed as

antibacterial dressingdrug deliveryhemicelluloseswound infection

Identifiers

PMID32138203
PMCPMC7183054
OpenAlexW3009734238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.