Evidence map›Paper›PMID 32138195›Full record

Trial reportBiomolecules2020

Altered Plasma Acylcarnitines and Amino Acids Profile in Spinocerebellar Ataxia Type 7.

Rafael Nambo-Venegas, Claudia Valdez-Vargas, Bulmaro Cisneros, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, César M Cerecedo-Zapata, Emilio Martínez-Cruz, Hernán Cortés, Juan P Reyes-Grajeda and 1 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. PathIN: an integrated tool for the visualization of pathway interaction networks.Computational and structural biotechnology journal · 2023
    Article
  8. Spinocerebellar ataxia clinical trials: opportunities and challenges.Annals of clinical and translational neurology · 2021
    Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Rafael Nambo-VenegasLaboratory of Chronic Diseases Biochemistry, National Genomics Medicine Institute (INMEGEN), Mexico City 14610, Mexico.
Claudia Valdez-VargasLaboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Mexico City 14389, Mexico.
Bulmaro CisnerosDepartment of Genetics and Molecular Biology, Center of Research and Advanced Studies (CINVESTAV-IPN), Mexico City 07360, Mexico.
Berenice Palacios-GonzálezScientific Bonding Unit, Medicine Faculty UNAM-INMEGEN, Mexico City 14610, Mexico.
Marcela Vela-AmievaLaboratory of Inborn errors of metabolism, National Pediatrics Institute (INP), Mexico City 04530, Mexico.
Isabel Ibarra-GonzálezInstitute of Biomedical Research, IIB-UNAM, Mexico City 04510, Mexico.
César M Cerecedo-ZapataRehabilitation and Special Education Center of Veracruz (CRISVER-DIF), Xalapa 91097, Veracruz, Mexico.
Emilio Martínez-CruzRehabilitation and Special Education Center of Veracruz (CRISVER-DIF), Xalapa 91097, Veracruz, Mexico.
Hernán CortésLaboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Mexico City 14389, Mexico.
Juan P Reyes-GrajedaLaboratory of Chronic Diseases Biochemistry, National Genomics Medicine Institute (INMEGEN), Mexico City 14610, Mexico.
Jonathan J MagañaLaboratory of Genomic Medicine, Department of Genetics, National Rehabilitation Institute (INR-LGII), Mexico City 14389, Mexico.
National Institute of Genomic Medicine · MXEl Colegio de Veracruz · MXCentro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXUniversidad Nacional Autónoma de México · MX

Funding

CONACyT 258043
6 · The paper itself

Abstract

Spinocerebellar ataxia type 7 (SCA7), a neurodegenerative disease characterized by cerebellar ataxia and retinal degeneration, is caused by an abnormal CAG repeat expansion in the

Indexed as

AdultAmino AcidsBiomarkersCarnitineFemaleHumansMaleMiddle AgedSpinocerebellar AtaxiasacylcarnitineAmino AcidsBiomarkersCarnitinebiomarkersCAG repeatsmetabolic pathwaysmetabolomicsmitochondrial diseasepolyglutamine diseasespinocerebellar ataxia 7

Identifiers

PMID32138195
PMCPMC7175318
OpenAlexW3009588034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.