Evidence map›Paper›PMID 32138181›Full record

ArticleViruses2020

IRE1α Promotes Zika Virus Infection via XBP1.

Elena P Kolpikova, Ana R Tronco, Andreas B den Hartigh, Konner J Jackson, Takao Iwawaki, Susan L Fink

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Evolution of Zika virus inVirus evolution · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Elena P KolpikovaDepartment of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA.
Ana R TroncoDepartment of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA.
Andreas B den HartighDepartment of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA.
Konner J JacksonDepartment of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA.
Takao IwawakiDivision of Cell Medicine, Department of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada, Ishikawa 920-0265, Japan.
Susan L FinkDepartment of Laboratory Medicine, University of Washington, Seattle, WA 98195, USA.ORCID 0000-0003-1705-0103
University of Washington · USKanazawa Medical University · JP

Funding

Role of Ire1alpha in Resistance to Viral-Induced ApoptosisK08AI119142 · NIAID · YALE UNIVERSITY · PI FINK, SUSAN LEILANI · 2015 to 2019
$922k
Leica SP8 WWL Confocal MicroscopeS10OD016240 · OD · UNIVERSITY OF WASHINGTON · PI CATTERALL, WILLIAM A · 2014 to 2014
$581k
Role of IRE1 Alpha in Zika Virus InfectionR21AI131269 · NIAID · UNIVERSITY OF WASHINGTON · PI FINK, SUSAN LEILANI · 2018 to 2019
$497k
National Institute of Allergy and Infectious Diseases K08AI119142National Institute of Allergy and Infectious Diseases R21AI131269NIAID NIH HHS K08 AI119142NIAID NIH HHS R21 AI131269NIH HHS S10 OD016240
6 · The paper itself

Abstract

Zika virus (ZIKV) is an emergent member of the

Indexed as

Host-Pathogen InteractionsAnimalsCells, CulturedChlorocebus aethiopsEndoplasmic ReticulumEndoplasmic Reticulum StressEndoribonucleasesHeLa CellsHumansProtein BindingProtein Serine-Threonine KinasesSignal TransductionVero CellsVirus ReplicationX-Box Binding Protein 1Zika VirusEndoribonucleasesERN1 protein, humanProtein Serine-Threonine KinasesX-Box Binding Protein 1endoplasmic reticulumER stressflavivirusIRE1αunfolded protein responseXBP1Zika virus

Identifiers

PMID32138181
PMCPMC7150863
OpenAlexW3009872770

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.