ArticleCancers2020
Serine Biosynthesis Pathway Supports MYC-miR-494-EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells.
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Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
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Who cites it
32 citing papers in PubMed, 63 citations in OpenAlex.
- Review
- Mechanical Loading Induces Distinct and Shared Responses in Endothelial and Muscle Cells and Reveals Exercise-Like Molecular Profiles.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Epigenetics and One-Carbon Metabolism in Cancer: Mechanisms and Therapeutic Implications.Advances in experimental medicine and biology · 2026Review
- Serine metabolism reprogramming in cancer: a multi-tiered regulatory framework.Acta biochimica et biophysica Sinica · 2025Review
- Methionine Dependency and Restriction in Cancer: Exploring the Pathogenic Function and Therapeutic Potential.Pharmaceuticals (Basel, Switzerland) · 2025Review
- PHGDH activation fuels glioblastoma progression and radioresistance via serine synthesis pathway.Journal of experimental & clinical cancer research : CR · 2025Article
- Cancer metabolism rewiring and chromatin methylation: a vulnerable epi-metabolic link.Frontiers in epigenetics and epigenomics · 2025Article
- Cellular Responses Induced by NCT-503 Treatment on Triple-Negative Breast Cancer Cell Lines: A Proteomics Approach.Biomedicines · 2024Article
- CRISPR screening identifies BET and mTOR inhibitor synergy in cholangiocarcinoma through serine glycine one carbon.JCI insight · 2024Article
- Glutaminolysis is a Potential Therapeutic Target for Kidney Diseases.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- KLF4 is an epigenetically modulated, context-dependent tumor suppressor.Frontiers in cell and developmental biology · 2024Review
- Regulatory mechanisms of one-carbon metabolism enzymes.The Journal of biological chemistry · 2023Review
- SIRT1 and HSP90α feed-forward circuit safeguards chromosome segregation integrity in diffuse large B cell lymphomas.Cell death & disease · 2023Article
- SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters.Cancers · 2023Article
- Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.Nature communications · 2023Article
- PSAT1 positively regulates the osteogenic lineage differentiation of periodontal ligament stem cells through the ATF4/PSAT1/Akt/GSK3β/β-catenin axis.Journal of translational medicine · 2023Article
- Metabolic Reprogramming in Hematologic Malignancies: Advances and Clinical Perspectives.Cancer research · 2022Review
- PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma.The Journal of clinical investigation · 2022Article
- Metabolic control of epigenetic rearrangements in B cell pathophysiology.Open biology · 2022Review
- The long and short non-coding RNAs modulating EZH2 signaling in cancer.Journal of hematology & oncology · 2022Review
Corrections and comments
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Authors and funding
28 authors at 6 institutions in 2 countries.
Emilia BiałopiotrowiczDepartment of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Monika Noyszewska-KaniaDepartment of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Neli Kachamakova-TrojanowskaDepartment of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, 30-387 Cracow, Poland.
Agnieszka ŁobodaDepartment of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, 30-387 Cracow, Poland.
Magdalena CybulskaDepartment of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland.ORCID 0000-0002-1029-3156
Aleksandra GrochowskaDepartment of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland.
Michał KopczyńskiDepartment of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland.
Michał MikulaDepartment of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, 02-781 Warsaw, Poland.
Monika Prochorec-SobieszekDepartment of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Małgorzata FirczukDepartment of Immunology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Agnieszka Graczyk-JarzynkaDepartment of Immunology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Radosław ZagożdżonDepartment of Clinical Immunology, Medical University of Warsaw, 02-006 Warsaw, Poland.
Adam ZąbekDepartment of Bioorganic Chemistry, Wroclaw University of Technology, 50-370 Wroclaw, Poland.
Piotr MłynarzDepartment of Bioorganic Chemistry, Wroclaw University of Technology, 50-370 Wroclaw, Poland.
Józef DulakDepartment of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Cracow, 30-387 Cracow, Poland.
Patryk GórniakDepartment of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Maciej SzydłowskiDepartment of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Karolina PyziakRyvu Therapeutics S.A., 30-348 Cracow, Poland.ORCID 0000-0003-4432-1888
Justyna MartykaRyvu Therapeutics S.A., 30-348 Cracow, Poland.
Agnieszka Sroka-PoradaRyvu Therapeutics S.A., 30-348 Cracow, Poland.
Ewa JabłońskaDepartment of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Anna PolakDepartment of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Piotr KowalczykRyvu Therapeutics S.A., 30-348 Cracow, Poland.
Anna Szumera-CiećkiewiczDepartment of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Bjoern ChapuyDepartment of Hematology and Oncology, University Medical Center Göttingen, 37-075 Göttingen, Germany.
Tomasz RzymskiRyvu Therapeutics S.A., 30-348 Cracow, Poland.
Krzysztof BrzózkaRyvu Therapeutics S.A., 30-348 Cracow, Poland.
Przemysław JuszczyńskiDepartment of Experimental Hematology, Institute of Hematology and Transfusion Medicine, 02-776 Warsaw, Poland.
Instytut Hematologii i Transfuzjologi · PLThe Maria Sklodowska-Curie National Research Institute of Oncology · PLJagiellonian University · PLMedical University of Warsaw · PLWrocław University of Science and Technology · PLUniversitätsmedizin Göttingen · DE
Funding
Narodowe Centrum Badań i Rozwoju STRATEGMED1/233574/15/NCBR/2015
Abstract
Burkitt lymphoma (BL) is a rapidly growing tumor, characterized by high anabolic requirements. The
Indexed as
Burkitt lymphomametabolismMYCserine biosynthesis pathway
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