Evidence map›Paper›PMID 32135118›Full record

ReviewThe Lancet. Oncology2020

Radiotheranostics: a roadmap for future development.

Ken Herrmann, Markus Schwaiger, Jason S Lewis, Stephen B Solomon, Barbara J McNeil, Michael Baumann, Sanjiv S Gambhir, Hedvig Hricak, Ralph Weissleder

Abstract readReview
In one paragraph

Review in The Lancet. Oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 143 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
143citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

143 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Pivotal Phase 3 Theranostic Trials: Future Indications.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Review
  5. Review
  6. Dual-Target Nectin-4/FAP Heterobivalent ProbeAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Comparative Study of NOTA-Derived Chelators: Synthesis, AlInternational journal of molecular sciences · 2026
    Article
  11. Review
  12. ImprovedACS omega · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. [Chemical & biomedical imaging · 2026
    Article
  17. Article
  18. Article
  19. Review
  20. Adsorption treatment ofAnnals of nuclear medicine · 2026
    Article

83 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ken HerrmannClinic for Nuclear Medicine, University Hospital Essen, Essen, Germany.
Markus SchwaigerDepartment of Nuclear Medicine, Klinikum Rechts der Isar, Technical University Munich, Munich, Germany.
Jason S LewisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.
Stephen B SolomonDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.
Barbara J McNeilDepartment of Radiology, Brigham and Women's Hospital, and Department of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Michael BaumannGerman Cancer Research Center (DKFZ), Heidelberg, Germany.
Sanjiv S GambhirDepartment of Radiology and Molecular Imaging Program, Stanford University, Stanford, CA, USA.
Hedvig HricakDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.
Ralph WeisslederDepartment of Radiology, and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: ralph_weissleder@hms.harvard.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Radiotheranostics, injectable radiopharmaceuticals with antitumour effects, have seen rapid development over the past decade. Although some formulations are already approved for human use, more radiopharmaceuticals will enter clinical practice in the next 5 years, potentially introducing new therapeutic choices for patients. Despite these advances, several challenges remain, including logistics, supply chain, regulatory issues, and education and training. By highlighting active developments in the field, this Review aims to alert practitioners to the value of radiotheranostics and to outline a roadmap for future development. Multidisciplinary approaches in clinical trial design and therapeutic administration will become essential to the continued progress of this evolving therapeutic approach.

Indexed as

AnimalsBiomedical ResearchDiffusion of InnovationForecastingHumansNeoplasmsRadiation OncologyRadiopharmaceuticalsTheranostic NanomedicineTreatment OutcomeRadiopharmaceuticals

Identifiers

PMID32135118
PMCPMC7367151

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.