Evidence map›Paper›PMID 32135090›Full record

ReviewNeuron2020

Conscious Processing and the Global Neuronal Workspace Hypothesis.

George A Mashour, Pieter Roelfsema, Jean-Pierre Changeux, Stanislas Dehaene

Abstract readReview
In one paragraph

Review in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 413 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
413citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

413 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  9. Recovery from disorders of consciousness: Lesions and GABAergic modulation in a biologically inspired spiking neural network.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  13. Review
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  15. The Emergence of Consciousness.Acta paediatrica (Oslo, Norway : 1992) · 2026
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353 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

George A MashourCenter for Consciousness Science, Neuroscience Graduate Program, and Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Pieter RoelfsemaDepartment of Vision & Cognition, Netherlands Institute for Neuroscience, Meibergdreef 47, 1105 BA, Amsterdam, the Netherlands; Department of Integrative Neurophysiology, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, the Netherlands; Department of Psychiatry, Academic Medical Center, Amsterdam, the Netherlands.
Jean-Pierre ChangeuxCNRS UMR 3571, Institut Pasteur, 75724 Paris, France; Collège de France, 11 Place Marcelin Berthelot, 75005 Paris, France; Kavli Institute for Brain & Mind, University of California, San Diego, La Jolla, CA, USA. Electronic address: changeux@noos.fr.
Stanislas DehaeneCollège de France, 11 Place Marcelin Berthelot, 75005 Paris, France; Cognitive Neuroimaging Unit, CEA, INSERM, Université Paris-Sud, Université Paris-Saclay, NeuroSpin Center, 91191 Gif/Yvette, France. Electronic address: stanislas.dehaene@gmail.com.

Funding

Role of the Prefrontal Cortex in the Control of Arousal StatesR01GM111293 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER, PAL, DINESH · 2015 to 2022
$2.6M
Frontoparietal Mechanisms of Anesthetic-induced UnconsciousnessR01GM098578 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, UNCHEOL, MASHOUR, GEORGE ALEXANDER · 2012 to 2019
$2.4M
NIGMS NIH HHS R01 GM098578NIGMS NIH HHS R01 GM111293
6 · The paper itself

Abstract

We review the central tenets and neuroanatomical basis of the global neuronal workspace (GNW) hypothesis, which attempts to account for the main scientific observations regarding the elementary mechanisms of conscious processing in the human brain. The GNW hypothesis proposes that, in the conscious state, a non-linear network ignition associated with recurrent processing amplifies and sustains a neural representation, allowing the corresponding information to be globally accessed by local processors. We examine this hypothesis in light of recent data that contrast brain activity evoked by either conscious or non-conscious contents, as well as during conscious or non-conscious states, particularly general anesthesia. We also discuss the relationship between the intertwined concepts of conscious processing, attention, and working memory.

Indexed as

Anesthesia, GeneralAttentionBrainCognitionConsciousnessHumansMemory, Short-TermNeuronsPsychological Theory

Identifiers

PMID32135090
PMCPMC8770991

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.