Evidence map›Paper›PMID 32134637›Full record

ArticleACS synthetic biology2020

Refactoring Ehrlich Pathway for High-Yield 2-Phenylethanol Production in

Yang Gu, Jingbo Ma, Yonglian Zhu, Peng Xu

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Fermentation Process Optimization for High 2-Phenylethanol Aroma Whisky.International journal of molecular sciences · 2026
    Article
  5. EngineeringFrontiers in microbiology · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Isolation and Identification of Non-Journal of fungi (Basel, Switzerland) · 2023
    Article
  17. A review of synthetic biology tools in Yarrowia lipolytica.World journal of microbiology & biotechnology · 2023
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Yang GuDepartment of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, Maryland 21250, United States.
Jingbo MaDepartment of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, Maryland 21250, United States.
Yonglian ZhuKey Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China.
Peng XuDepartment of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, Maryland 21250, United States.ORCID 0000-0002-0999-8546
Jiangnan University · CNUniversity of Maryland, Baltimore County · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient microbial synthesis of chemicals requires the coordinated supply of precursors and cofactors to maintain cell growth and product formation. Substrates with different entry points into the metabolic network have different energetic and redox statuses. Generally, substrate cofeeding could bypass the lengthy and highly regulated native metabolism and facilitates high carbon conversion rate. Aiming to efficiently synthesize the high-value rose-smell 2-phenylethanol (2-PE) in

Indexed as

Alcohol OxidoreductasesCarboxy-LyasesGlucoseKetoglutaric AcidsMetabolic EngineeringMetabolic Networks and PathwaysMicroorganisms, Genetically-ModifiedPhenylalaninePhenylethyl AlcoholTransaminasesYarrowiaAlcohol OxidoreductasesCarboxy-LyasesGlucoseKetoglutaric Acidsphenylacetaldehyde reductasePhenylalaninePhenylethyl Alcoholphenylpyruvate decarboxylaseTransaminases2-phenylethanolcofactor engineeringEhrlich pathwaypathway selectivitystoichiometric modelYarrowia lipolytica

Identifiers

PMID32134637
PMCPMC7308069
OpenAlexW3010506089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.