Evidence map›Paper›PMID 32134478›Full record

ReviewThe Journal of infectious diseases2020

The Status of Vaccine Development Against the Human Cytomegalovirus.

Stanley A Plotkin, Dai Wang, Abdel Oualim, Don J Diamond, Camille N Kotton, Sally Mossman, Andrea Carfi, David Anderson, Philip R Dormitzer

Abstract readReview
In one paragraph

Review in The Journal of infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. An OralPathogens (Basel, Switzerland) · 2025
    Article
  12. Review
  13. Article
  14. Oral Vaccination with AttenuatedPathogens (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Article
  17. A vaccine against cytomegalovirus: how close are we?The Journal of clinical investigation · 2025
    Article
  18. Article
  19. Review
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stanley A PlotkinDepartment of Pediatrics, University of Pennsylvania, Vaxconsult, Doylestown, Pennsylvania, USA.
Dai WangMerck & Co., Kenilworth, New Jersey, USA.
Abdel OualimSanofi-Pasteur, Swiftwater, Pennsylvania, USA.
Don J DiamondCity of Hope National Medical Center, Duarte, California, USA.
Camille N KottonMassachusetts General Hospital, Boston, Massachusetts, USA.
Sally MossmanGlaxoSmithKline Vaccines, Rockville, Maryland, USA.
Andrea CarfiModerna Therapeutics, Cambridge, Massachusetts, USA.
David AndersonVBI Vaccines, Cambridge, Massachusetts, USA.
Philip R DormitzerPfizer Vaccines, Pearl River, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous candidate vaccines against cytomegalovirus (CMV) infection and disease are in development. Whereas the previous article [1] provides background and opinions about the issues relating to vaccination, this article provides specifics about the vaccines in active development, as reported at a National Institutes of Health-sponsored meeting in Bethesda on September 4-6, 2018. Here, vaccine developers provide synopses of their candidate vaccines to immunize women to protect against congenital CMV disease and to prevent the consequences of CMV disease in recipients of transplanted organs or hematopoietic stem calls. The projects are presented here roughly in the descending order of their stage of development in the opinion of the first author.

Indexed as

AnimalsClinical Trials as TopicCytomegalovirusCytomegalovirus InfectionsCytomegalovirus VaccinesDrug Evaluation, PreclinicalHumansOrgan TransplantationPatient Outcome AssessmentStem Cell TransplantationVaccinationCytomegalovirus Vaccinescytomegalovirusfetal infectionorgan transplantstem cell transplant

Identifiers

PMID32134478
PMCPMC7057802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.