ArticleeLife2020
Cell type composition and circuit organization of clonally related excitatory neurons in the juvenile mouse neocortex.
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Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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32citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
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Who cites it
32 citing papers in PubMed, 52 citations in OpenAlex.
- Direct and indirect neurogenesis from radial glial progenitor cell clones in the mouse neocortex.The EMBO journal · 2026Article
- Combined somatic mutation and transcriptome analysis reveals region-specific differences in clonal architecture in human cortex.Cell reports · 2025Article
- Deep learning-driven characterization of single cell tuning in primate visual area V4 supports topological organization.bioRxiv : the preprint server for biology · 2025Article
- A detailed theory of thalamic and cortical microcircuits for predictive visual inference.Science advances · 2025Article
- Molecular logic for cellular specializations that initiate the auditory parallel processing pathways.Nature communications · 2025Article
- Clonal Tracking in the Mouse Brain with Single-Cell RNA-Seq.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Implementation and validation of single-cell genomics experiments in neuroscience.Nature neuroscience · 2024Review
- Molecular logic for cellular specializations that initiate the auditory parallel processing pathways.bioRxiv : the preprint server for biology · 2024Article
- Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex.Neuron · 2024Review
- Linear and Nonlinear Behaviors of the Photoreceptor Coupled Network.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Multimodal Nature of the Single-cell Primate Brain Atlas: Morphology, Transcriptome, Electrophysiology, and Connectivity.Neuroscience bulletin · 2024Review
- Integrating single-cell transcriptomics with cellular phenotypes: cell morphology, CaBiophysical reviews · 2024Review
- Molecular and functional profiling of cell diversity and identity in the lateral superior olive, an auditory brainstem center with ascending and descending projections.Frontiers in cellular neuroscience · 2024Article
- Patch-seq: Advances and Biological Applications.Cellular and molecular neurobiology · 2023Review
- Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types and cortical areas in human cerebral cortex.bioRxiv : the preprint server for biology · 2023Article
- Hierarchical Modular Structure of theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Determinants of functional synaptic connectivity among amygdala-projecting prefrontal cortical neurons in male mice.Nature communications · 2023Article
- Loss or gain of function? Effects of ion channel mutations on neuronal firing depend on the neuron type.Frontiers in neurology · 2023Article
- Article
- Identification of TPBG-Expressing Amacrine Cells in DAT-tdTomato Mouse.Investigative ophthalmology & visual science · 2022Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 3 countries.
Cathryn R CadwellDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.ORCID 0000-0003-1963-8285
Federico ScalaDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.
Paul G FaheyDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.
Dmitry KobakInstitute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-5639-7209
Shalaka MulherkarDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.ORCID 0000-0001-8736-527X
Fabian H SinzDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-1348-9736
Stelios PapadopoulosDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.
Zheng H TanDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.
Per JohnssonDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Leonard HartmanisDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Shuang LiDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.
Ronald J CottonDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.
Kimberley F ToliasDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-2092-920X
Rickard SandbergDepartment of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.
Philipp BerensInstitute for Ophthalmic Research, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-0199-4727
Xiaolong JiangDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.
Andreas Savas ToliasDepartment of Neuroscience, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-4305-6376
Baylor College of Medicine · USKarolinska Institutet · SEUniversity of Tübingen · DEUniversity of California, San Francisco · US
Funding
Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI NGAI, JOHN J. · 2017 to 2021
$64.7MMEDICAL SCIENTIST TRAINING PROGRAMT32GM007330 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI PLON, SHARON E. · 1985 to 2019
$15.6MVISION RESEARCH CENTERP30EY002520 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$14.8MVISUAL SCIENCEST32EY007001 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$3.7MDeciphering the building blocks of hippocampal circuitsR01MH109556 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI SANDBERG, RICKARD, TOLIAS, ANDREAS · 2017 to 2021
$3.3MDissecting the Fabric of the Cerebral CortexDP1EY023176 · NEI · BAYLOR COLLEGE OF MEDICINE · PI TOLIAS, ANDREAS · 2012 to 2015
$3.1MDeciphering the building blocks of the macaque prefrontal cortical microcircuitR01MH120404 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI JIANG, XIAOLONG · 2019 to 2023
$2.0MA MOLECULAR CODE FOR CONNECTIVITY IN THE NEOCORTEXR01MH103108 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI TOLIAS, ANDREAS, TOLIAS, KIMBERLY R · 2013 to 2016
$1.3MOptogenetic Tools for in vivo Analysis of Cortical Circuit PlasticityR01DA028525 · NIDA · BAYLOR COLLEGE OF MEDICINE · PI SAGGAU, PETER, TOLIAS, ANDREAS · 2009 to 2010
$1.2MDeciphering the transcriptomic signatures, physiology, and connectivity of the specialized morphotypes in macaque insular cortexR01MH122169 · NIMH · BAYLOR COLLEGE OF MEDICINE · PI JIANG, XIAOLONG · 2020 to 2024
$1.2MDissecting the Fabric of the Cerebral CortexDP1OD008301 · OD · BAYLOR COLLEGE OF MEDICINE · PI TOLIAS, ANDREAS · 2011 to 2011
$783kTraining in Theoretical and Computational NeuroscienceT32EB006350 · NIBIB · BAYLOR COLLEGE OF MEDICINE · PI SAGGAU, PETER · 2007 to 2011
$693kNEI NIH HHS DP1 EY023176NEI NIH HHS P30 EY002520NEI NIH HHS T32 EY007001NIBIB NIH HHS T32 EB006350NIDA NIH HHS R01 DA028525NIGMS NIH HHS T32 GM007330NIH HHS DP1 OD008301NIMH NIH HHS F30 MH095440NIMH NIH HHS F30 MH112312NIMH NIH HHS R01 MH103108NIMH NIH HHS R01 MH109556NIMH NIH HHS R01 MH120404NIMH NIH HHS R01 MH122169NIMH NIH HHS U19 MH114830
Abstract
Clones of excitatory neurons derived from a common progenitor have been proposed to serve as elementary information processing modules in the neocortex. To characterize the cell types and circuit diagram of clonally related excitatory neurons, we performed multi-cell patch clamp recordings and Patch-seq on neurons derived from
Indexed as
AnimalsCells, CulturedMiceNeocortexNeuronsSynapsescell lineageclonally relatedconnectivitycortical developmentdevelopmental biologyexcitatory neuronsmouseneurosciencetranscriptomics
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