Evidence map›Paper›PMID 32134178›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2020

Percutaneous coronary intervention for left main stem disease: Impact of diabetes mellitus on mortality.

Bilal R Bawamia, Mohaned Egred, Matthew Jackson, Ian Purcell, David Austin, Azfar G Zaman

Open access · hybridAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Treatment of Left Main Disease: Let the Patient Choose.Journal of the American Heart Association · 2021
    Article
  2. Percutaneous coronary intervention for left main stem disease: Impact of diabetes mellitus on mortality.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bilal R BawamiaCardiology Department, James Cook University Hospital, Middlesbrough, UK.ORCID 0000-0003-4460-7544
Mohaned EgredCardiology Department, Freeman Hospital, Newcastle upon Tyne, UK.
Matthew JacksonCardiology Department, James Cook University Hospital, Middlesbrough, UK.
Ian PurcellCardiology Department, Freeman Hospital, Newcastle upon Tyne, UK.
David AustinCardiology Department, James Cook University Hospital, Middlesbrough, UK.
Azfar G ZamanCardiology Department, Freeman Hospital, Newcastle upon Tyne, UK.
Freeman Hospital · GBJames Cook University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe assessed the impact of diabetes mellitus (DM) on mortality after percutaneous coronary intervention (PCI) for left main stem (LMS) disease. Second, we compared mortality outcomes between non-insulin treated (NITDM) and insulin treated diabetes (ITDM) in different clinical settings.

backgroundThere is a paucity of "real world" outcomes data in diabetic patients undergoing LMS PCI.

methodsWe undertook a retrospective analysis of consecutive patients undergoing unprotected LMS PCI at 2 high volume tertiary centers. Diabetic status and clinical setting for PCI were recorded. The primary outcome measure was all-cause 30-day and long-term mortality (up to 36 months) post index PCI.

resultsBetween 2003 and 2017, 2,675 patients undergoing index LMS PCI were analyzed. Of those, 77.1% were non-DM, 15.8% NITDM, and 7.1% ITDM. Overall, DM status was not associated with higher 30-day mortality (OR 1.39, 95% CI 0.89-2.16, p = .15). During a median follow-up of 36 months, there was a borderline statistical association of DM with long-term mortality in all PCI settings (HR 1.31, 95% CI 1.00-1.71, p = .05). Compared to non-DM, ITDM but not NITDM was associated with short- and long-term mortality in all clinical presentations.

conclusionsOverall, DM did not impact on 30-day mortality and had only a borderline statistical association with long-term mortality. It did not have an influence on mortality in non-emergency LMS PCI. The impact of DM on mortality outcomes following LMS PCI was only significant in the insulin treated patients.

Indexed as

Percutaneous Coronary InterventionAgedCoronary Artery DiseaseDatabases, FactualDiabetes MellitusEnglandFemaleHumansHypoglycemic AgentsInsulinMaleRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeHypoglycemic AgentsInsulindiabetes mellitusleft Main Coronary Diseasepercutaneous Coronary Intervention

Identifiers

PMID32134178
PMCPMC7687181
OpenAlexW3009698396

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.