Evidence map›Paper›PMID 32133993›Full record

ArticleActa crystallographica. Section D, Structural biology2020

Structural evidence for a latch mechanism regulating access to the active site of SufS-family cysteine desulfurases.

Jack A Dunkle, Michael R Bruno, Patrick A Frantom

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section D, Structural biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jack A DunkleDepartment of Chemistry and Biochemistry, University of Alabama, 250 Hackberry Lane, Tuscaloosa, AL 35401, USA.
Michael R BrunoDepartment of Chemistry and Biochemistry, University of Alabama, 250 Hackberry Lane, Tuscaloosa, AL 35401, USA.
Patrick A FrantomDepartment of Chemistry and Biochemistry, University of Alabama, 250 Hackberry Lane, Tuscaloosa, AL 35401, USA.
University of Alabama · US

Funding

Conformational dynamics and allosteric regulation during stress-responsive metallocofactor assemblyR01GM112919 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI Patrick Frantom · 2015 to 2026
$2.8M
NIGMS NIH HHS R01 GM112919NIH HHS GM112919NIH HHS S10_RR028976NIH HHS S10_RR25528U.S. Department of Energy W-31-109-Eng-38
6 · The paper itself

Abstract

Cysteine serves as the sulfur source for the biosynthesis of Fe-S clusters and thio-cofactors, molecules that are required for core metabolic processes in all organisms. Therefore, cysteine desulfurases, which mobilize sulfur for its incorporation into thio-cofactors by cleaving the C

Indexed as

Catalytic DomainAmino Acid SequenceCarbon-Sulfur LyasesCrystallography, X-RayDimerizationEscherichia coli ProteinsSulfurCarbon-Sulfur Lyasescysteine desulfuraseEscherichia coli ProteinsSulfurcysteine desulfuraseFe–S clusterSufSsulfur

Identifiers

PMID32133993
PMCPMC7057215
OpenAlexW3009468223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.