Evidence map›Paper›PMID 32133616›Full record

ArticleBritish journal of pharmacology2020

Gonadal hormone-independent sex differences in GABA

Franco R Mir, Carlos Wilson, Lucas E Cabrera Zapata, Luis G Aguayo, María Julia Cambiasso

Open access · hybridAbstract read
In one paragraph

Article in British journal of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Mitochondrial dysfunction and CaScientific reports · 2026
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  9. Gonadal hormone-independent sex differences in GABABritish journal of pharmacology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Franco R MirLaboratorio de Neurofisiología, Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, Córdoba, Argentina.ORCID 0000-0001-9327-7751
Carlos WilsonLaboratorio de Neurobiología, Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, Córdoba, Argentina.
Lucas E Cabrera ZapataLaboratorio de Neurofisiología, Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, Córdoba, Argentina.
Luis G AguayoDepartamento de Fisiología, Facultad de Ciencias Biológicas, Universidad de Concepción, Concepción, Chile.ORCID 0000-0003-3160-1522
María Julia CambiassoLaboratorio de Neurofisiología, Instituto de Investigación Médica Mercedes y Martín Ferreyra, INIMEC-CONICET, Universidad Nacional de Córdoba, Córdoba, Argentina.ORCID 0000-0002-3738-4699
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Concepción · CL

Funding

Fondecyt 1180753Fondo para la Investigación Científica y Tecnológica PICT 2015 N° 1333Proyectos de Investigación Plurianuales PIP 2013-2015Secretaría de Ciencia y Tecnología 00-10460/2015Secretaría de Ciencia y Tecnología SECyT-UNC, 2018-2021
6 · The paper itself

Abstract

background and purposeGABA EXPERIMENTAL APPROACH: Ventromedial hypothalamic neurons were obtained from embryonic day 16 rat brains and grown in vitro for 2 days. Calcium imaging and electrophysiology recordings were carried out to assess GABA KEY

resultsGABA CONCLUSION AND IMPLICATIONS: GABA-mediated responses are sexually dimorphic even in the absence of gonadal hormone influence, suggesting genetically biased differences. These results highlight the importance of GABA

Indexed as

Receptors, GABA-ASex CharacteristicsAnimalsFemaleGonadal HormonesHypothalamusMaleNeuronsRatsGonadal HormonesReceptors, GABA-A

Identifiers

PMID32133616
PMCPMC7280008
OpenAlexW3009512102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.