Evidence map›Paper›PMID 32133587›Full record

ArticleObesity surgery2020

Impact of Postprandial Hypoglycemia on Weight Loss After Bariatric Surgery.

Eleni Rebelos, Diego Moriconi, Marco Scalese, Francesca Denoth, Sabrina Molinaro, Valeria Siciliano, Marco Anselmino, Stefano Taddei, Ele Ferrannini, Monica Nannipieri

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In one paragraph

Article in Obesity surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.

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  13. Bariatric surgery to treat hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Eleni RebelosDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy. eleni.rebelos@utu.fi.ORCID http://orcid.org/0000-0003-3050-8692
Diego MoriconiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Marco ScaleseCNR Institute of Clinical Physiology, Pisa, Italy.
Francesca DenothCNR Institute of Clinical Physiology, Pisa, Italy.
Sabrina MolinaroCNR Institute of Clinical Physiology, Pisa, Italy.
Valeria SicilianoCNR Institute of Clinical Physiology, Pisa, Italy.
Marco AnselminoUnit of Bariatric Surgery, AOUP, Pisa, Italy.
Stefano TaddeiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Ele FerranniniCNR Institute of Clinical Physiology, Pisa, Italy.
Monica NannipieriDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Istituto di Fisiologia Clinica · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPostprandial hypoglycemia (PPHG) is a well-known complication after bariatric surgery (BS). However, it is not known whether PPHG affects weight loss after BS.

aimsTo assess the impact of PPHG on weight loss after BS in subjects without and with type 2 diabetes mellitus (T2D).

methodsData from 338 subjects who had undergone gastric bypass (RYGB) or sleeve gastrectomy (LSG) and were followed up for at least 2 years were analyzed. At each follow-up visit, the patient's anthropometric and biochemical characteristics were recorded and the Edinburgh Questionnaire was performed to evaluate the presence of PPHG symptoms.

resultsBefore surgery: younger age and lower BMI predicted PPHG after BS (p = 0.02 and p = 0.0008, respectively). Also, the baseline OGTT indicated that subjects who developed PPHG had an earlier glucose peak and more often had low glucose levels at 2 h compared with the no-PPHG group (p = 0.03 and p = 0.004, respectively). After surgery: Mild-to-moderate PPHG occurred equally after RYGB and LSG (38% vs 25%, p = ns when accounting for confounders), and in T2D who achieved remission and those who did not (29.5% vs 28.6%, ns). At the 2-year follow-up, occurrence of PPHG was independently associated with smaller weight loss (p = 0.0006).

conclusionsMild-to-moderate PPHG is a frequent complication after bariatric surgery and results in smaller weight loss after 2 years. Age, baseline BMI, and an earlier glucose peak during OGTT predict PPHG after bariatric surgery.

Indexed as

Bariatric SurgeryDiabetes Mellitus, Type 2Gastric BypassHypoglycemiaObesity, MorbidGastrectomyHumansRetrospective StudiesTreatment OutcomeWeight LossBariatric surgeryPostprandial hypoglycemiaRYGBSleeve gastrectomyWeight loss

Identifiers

PMID32133587
OpenAlexW3009476061

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.