Evidence map›Paper›PMID 32133564›Full record

ArticleClinical rheumatology2020

Impact of Ramadan diurnal intermittent fasting on rheumatic diseases.

Dorra Ben Nessib, Kaouther Maatallah, Hanene Ferjani, Dhia Kaffel, Wafa Hamdi

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  7. Effects of Fasting on THP1 Macrophage Metabolism and Inflammatory Profile.International journal of molecular sciences · 2024
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  10. Rheumatoid Arthritis and Reactive Oxygen Species: A Review.Current issues in molecular biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dorra Ben NessibRheumatology Department, Kassab Orthopedics Institute, Mannouba, Tunisia. bennessibdorra@gmail.com.ORCID http://orcid.org/0000-0002-6284-5856
Kaouther MaatallahRheumatology Department, Kassab Orthopedics Institute, Mannouba, Tunisia.
Hanene FerjaniRheumatology Department, Kassab Orthopedics Institute, Mannouba, Tunisia.
Dhia KaffelRheumatology Department, Kassab Orthopedics Institute, Mannouba, Tunisia.
Wafa HamdiRheumatology Department, Kassab Orthopedics Institute, Mannouba, Tunisia.
Tunis University · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRamadan intermittent fasting is observed by Muslims from sunrise to sunset and alternated with moments of re-feeding. The aims of this study were to assess the impact of Ramadan fasting on rheumatoid arthritis (RA) and spondyloarthritis (SpA) activity and to assess its impact on chronic medications intake in patients with rheumatic diseases.

methodsThis prospective monocentric study included patients with RA or SpA who fasted during Ramadan of 2019. The disease activity and the managing of chronic medications were assessed and compared between two visits: the first one 6 months before starting Ramadan fasting and the second after fasting at least 7 days.

resultsFifty-six patients were included: 36 with RA (average age 57.5 ± 10.9 years) and 20 with SpA (average age 47 ± 12.6 years). In the RA group, the Disease Activity Scores (DAS) 28 ESR, and DAS 28 CRP decreased after fasting respectively from 4.3 ± 1.3 to 3.5 ± 1.4 (p < 0.001) and from 3.4 ± 1.2 to 2.9 ± 1.3 (p = 0.001). In the SpA group, Ankylosing Spondylitis Disease Activity Scores (ASDAS) ESR and ASDAS CRP decreased respectively from 2.3 ± 0.5 to 1.9 ± 0.7 (p = 0.039) and from 1.9 ± 0.5 to 1.8 ± 0.8 (p = 0.388). Fasting did not affect significantly either compliance with chronic medications or tolerance.

conclusionsFasting can be a possible way to induce rapid improvement of rheumatic diseases activity. In addition, patients with a specific fear of drug intake during this period can be reassured, which will enhance the adherence to treatment. Key Points • Fasting during Ramadan, the ninth month of the Islamic calendar, consists of intermittent fasting observed from sunrise to sunset. • In this set of patients, beneficial effects of intermittent fasting were demonstrated on RA activity, but were less evident in patients with SpA despite a general trend towards improvement. • Fasting did not affect significantly either compliance with chronic medications or tolerance.

Indexed as

FastingIslamMedication AdherenceAdultAgedArthritis, RheumatoidFemaleHumansMaleMiddle AgedProspective StudiesSeverity of Illness IndexSpondylarthritisTunisiaYoung AdultDisease activityDrugsFastingRheumatoid arthritisSpondyloarthritis

Identifiers

PMID32133564
OpenAlexW3010501324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.