Evidence map›Paper›PMID 32133537›Full record

SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2021

Midflexion instability in total knee arthroplasty: a systematic review.

Umile Giuseppe Longo, Vincenzo Candela, Francesco Pirato, Michael T Hirschmann, Roland Becker, Vincenzo Denaro

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Metaphyseal cones and sleeves are similar in improving short- and mid-term outcomes in Total Knee Arthroplasty revisions.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
    Pooled it
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  4. Review
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  6. Article
  7. Mid-term performance of a unicompartmental knee prosthesis.Journal of experimental orthopaedics · 2026
    Article
  8. Kinematic alignment doesn't tell the whole story: It's time for kinetic alignment.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025
    Article
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  20. Improved total knee arthroplasty pain outcome when joint gap targets are achieved throughout flexion.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Umile Giuseppe LongoDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Alvaro del, Portillo, 200, Trigoria, 00128, Rome, Italy. g.longo@unicampus.it.ORCID http://orcid.org/0000-0003-4063-9821
Vincenzo CandelaDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Alvaro del, Portillo, 200, Trigoria, 00128, Rome, Italy.
Francesco PiratoDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Alvaro del, Portillo, 200, Trigoria, 00128, Rome, Italy.
Michael T HirschmannDepartment of Orthopaedic Surgery and Traumatology, Kantonsspital Baselland (Bruderholz, Liestal, Laufen), 4101, Bruderholz, Switzerland.
Roland BeckerDepartment of Orthopaedic and Traumatology, Brandenburg Medical School Theodor Fontane, Hochstrasse 29, 14770, Brandenburg/Havel, Germany.
Vincenzo DenaroDepartment of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Alvaro del, Portillo, 200, Trigoria, 00128, Rome, Italy.
Università Campus Bio-Medico · ITKantonsspital Baselland Standort Bruderholz · CHMedizinische Hochschule Brandenburg Theodor Fontane · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this systematic review was to evaluate the evidence on the existence of midflexion instability in primary total knee arthroplasty and which factors might contribute to this condition.

methodsA comprehensive search of PubMed, Medline, Cochrane, CINAHL, and Embase databases was conducted since the inception of the database to July 2019. All relevant articles were retrieved, and their bibliographies were hand searched for further references on midflexion instability in primary total knee arthroplasty. The search strategy yielded 28 articles. After duplicate removal titles, abstracts and full text were reviewed. Fifteen studies were assessed for eligibility, 8 studies were excluded because they did not fully comply with the inclusion criteria. Seven articles were finally included in this systematic review. Anteroposterior translation, total knee arthroplasty design such as posterior-stabilized or posterior-cruciate-retaining total knee arthroplasty, joint line position with posterior condylar offset and joint gaps were considered to significantly influence midflexion stability.

resultsBased on this systematic review anteroposterior translation of ≥ 7 mm was an independent risk factor for midflexion instability at 30° knee flexion. Joint line position can be altered by up to 5 mm without measurable changes in joint stability and both an increase and a decrease in posterior condylar offset led to 30° midflexion instability.

conclusionMidflexion instability in primary total knee arthroplasty remains to be not entirely understood. Due to the low quality of available evidence, it is difficult to make any definitive conclusions. The factors which can lead to this condition were analyzed in this review, furthermore, we did not find exhaustive evidence on midflexion instability existence as an isolated entity. Nonetheless, this review will form a baseline for future research and creates awareness for the routine assessment of midflexion instability in primary total knee arthroplasty. LEVEL OF EVIDENCE: IV.

Indexed as

AgedArthroplasty, Replacement, KneeBiomechanical PhenomenaFemaleFemurHumansJoint InstabilityKnee JointMaleOsteoarthritis, KneeRange of Motion, ArticularRisk FactorsTibiaMidflexion instabilityMid flexion laxityMid range instabilityTotal knee arthroplastyTotal knee replacement

Identifiers

PMID32133537
OpenAlexW3010546472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.