ArticleJournal of experimental botany2020
Overexpression of bHLH95, a basic helix-loop-helix transcription factor family member, impacts trichome formation via regulating gibberellin biosynthesis in tomato.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 66 citations in OpenAlex.
- Article
- Comparative proteomics analysis of wild and cultivated accessions reveals key candidate proteins associated with seed weight variations in peanut.BMC plant biology · 2026Article
- The C2H2-type zinc finger protein SlHair5 acts as a regulatory node coordinating trichome development and leaf morphogenesis in tomato.Plant cell reports · 2026Article
- Article
- Insight into the genetic network governing long-stalked glandular trichome development in Nicotiana tabacum.Planta · 2025Article
- JA-Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8-SlWRKY57-SlAVT6s Module in Tomato.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Unraveling the Complexity of Plant Trichomes: Models, Mechanisms, and Bioengineering Strategies.International journal of molecular sciences · 2025Review
- Bi-functional transcription factor SlbHLH95 regulates fruits flavonoid metabolism and grey mould resistance in tomato.Plant biotechnology journal · 2025Article
- Genome- and Transcriptome-Wide Characterization and Expression Analyses of bHLH Transcription Factor Family Reveal Their Relevance to Salt Stress Response in Tomato.Plants (Basel, Switzerland) · 2025Article
- Review
- Multi-omics analysis of organ-specific hormone distribution and molecular regulatory mechanisms inFrontiers in plant science · 2025Article
- Regulatory mechanisms of trichome and root hair development in Arabidopsis.Plant molecular biology · 2024Review
- GhSBI1, a CUP-SHAPED COTYLEDON 2 homologue, modulates branch internode elongation in cotton.Plant biotechnology journal · 2024Article
- Research on the Mechanisms of Phytohormone Signaling in Regulating Root Development.Plants (Basel, Switzerland) · 2024Review
- Comparative transcriptome analysis reveals genes involved in trichome development and metabolism in tobacco.BMC plant biology · 2024Article
- Transcriptome Analysis Reveals Key Genes Involved in Trichome Formation in PepperPlants (Basel, Switzerland) · 2024Article
- A large presence/absence variation in the promotor of the ClLOG gene determines trichome elongation in watermelon.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Spatiotemporal formation of glands in plants is modulated by MYB-like transcription factors.Nature communications · 2024Article
- Article
- Advances in understanding epigenetic regulation of plant trichome development: a comprehensive review.Horticulture research · 2023Article
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Authors and funding
13 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trichomes are epidermal protuberances on aerial parts of plants known to play an important role in biotic and abiotic stresses. To date, our knowledge of the regulation of trichome formation in crop species is very limited. Through phenotyping of the Solanum pennellii×S. lycopersicum (cv. M82) introgression population, we identified the SlbHLH95 transcription factor as a negative regulator of trichome formation in tomato. In line with this negative role, SlbHLH95 displayed a very low expression in stems where trichomes are present at high density. Overexpression of SlbHLH95 resulted in a dramatically reduced trichome density in stems and a significant down-regulation of a set of trichome-related genes. In addition to the lower trichome density, overexpressing lines also showed pleiotropic alterations affecting both vegetative and reproductive development. While most of these phenotypes were reminiscent of gibberellin (GA)-deficient phenotypes, expression studies showed that two GA biosynthesis genes, SlGA20ox2 and SlKS5, are significantly down-regulated in SlbHLH95-OE plants. Moreover, in line with a decrease in active GA content, the glabrous and dwarf phenotypes were rescued by exogenous GA treatment. In addition, yeast one-hybrid and transactivation assays revealed that SlbHLH95 represses the expression of SlGA20ox2 and SlKS5 via direct binding to their promoters. Taken together, our study established a link between SlbHLH95, GA, and trichome formation, and uncovered the role of this gene in modulating GA biosynthesis in tomato.
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