Evidence map›Paper›PMID 32133424›Full record

ArticleNanoImpact2019

Dispersion preparation, characterization, and dosimetric analysis of cellulose nano-fibrils and nano-crystals: Implications for cellular toxicological studies.

Dimitrios Bitounis, Georgios Pyrgiotakis, Douglas Bousfield, Philip Demokritou

Abstract read
In one paragraph

Article in NanoImpact, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dimitrios BitounisCenter for Nanotechnology and Nanotoxicology, HSPH-NIEHS Nanosafety Center, Department of Environmental Health, Harvard T. H. Chan School of Public School, Harvard University, 665 Huntington Boston, MA 02115, USA.
Georgios PyrgiotakisCenter for Nanotechnology and Nanotoxicology, HSPH-NIEHS Nanosafety Center, Department of Environmental Health, Harvard T. H. Chan School of Public School, Harvard University, 665 Huntington Boston, MA 02115, USA.
Douglas BousfieldDepartment of Chemical and Biological Engineering, University of Maine, Orono, ME 04469, USA.
Philip DemokritouCenter for Nanotechnology and Nanotoxicology, HSPH-NIEHS Nanosafety Center, Department of Environmental Health, Harvard T. H. Chan School of Public School, Harvard University, 665 Huntington Boston, MA 02115, USA.
Harvard University · USUniversity of Maine · US

Funding

Engineered Nanomaterial Synthesis, Characterization and Method Development Center for Nano-safety ResearchU24ES026946 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI DEMOKRITOU, PHILIP · 2016 to 2020
$3.8M
NIEHS NIH HHS U24 ES026946
6 · The paper itself

Abstract

The characterization of cellulose-based nanomaterial (CNM) suspensions in environmental and biological media is impaired because of their high carbon content and anisotropic shape, thus making it difficult to derive structure activity relationships (SAR) in toxicological studies. Here, a standardized method for the dispersion preparation and characterization of cellulose nanofibrils (CNF) and nanocrystals (CNC) in biological and environmental media was developed. Specifically, electron microscopy was utilized and allowed to specify optimum practices for efficiently suspending CNF and CNC in water and cell culture medium. Furthermore, a technique for measuring the

Indexed as

nanocellulosenanocrystalsnanofibrilsnanotoxicologyparticle kinetics

Identifiers

PMID32133424
PMCPMC7055660
OpenAlexW2947339467

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.