Evidence map›Paper›PMID 32133407›Full record

ArticleScience advances2020

Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2.

Yong Fu, Yan Ding, Qinghui Wang, Feng Zhu, Yulong Tan, Xiao Lu, Bo Guo, Qingfeng Zhang, Yaming Cao, Taiping Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

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  9. Human transcriptional signature of protection afterHuman vaccines & immunotherapeutics · 2023
    Article
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  16. Article
  17. The role of Fibrinogen-like proteins in Cancer.International journal of biological sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yong FuDepartment of Pathogenic Biology, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.ORCID 0000-0001-6480-1147
Yan DingDepartment of Pathogenic Biology, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.
Qinghui WangDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, Liaoning, P.R. China.
Feng ZhuDepartment of Pathogenic Biology, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.
Yulong TanDepartment of Tropical Medicine, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.ORCID 0000-0002-9296-8064
Xiao LuDepartment of Pathogenic Biology, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.
Bo GuoDepartment of Pathogenic Biology, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.
Qingfeng ZhangResearch Center for Translational Medicine, Key Laboratory of Arrhythmias of the Ministry of Education of China, East Hospital, Tongji University School of Medicine, Shanghai, P.R. China.
Yaming CaoDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, Liaoning, P.R. China.
Taiping LiuDepartment of Pathogenic Biology, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.ORCID 0000-0003-2261-1155
Liwang CuiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA.ORCID 0000-0002-8338-1974
Wenyue XuDepartment of Pathogenic Biology, Army Medical University (The Third Military Medical University), Chongqing 400038, P.R. China.ORCID 0000-0003-3681-5052
Army Medical University · CNShenyang Medical College · CNTongji University · CNUniversity of South Florida · US

Funding

Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
NIAID NIH HHS U19 AI089672
6 · The paper itself

Abstract

Malaria parasites suppress host immune responses to facilitate their survival, but the underlying mechanism remains elusive. Here, we found that blood-stage malaria parasites predominantly induced CD4

Indexed as

Immunity, InnateAnimalsFemaleFibrinogenHumansMacrophagesMalaria, FalciparumMaleMiceMice, KnockoutPlasmodium falciparumFGL2 protein, humanFgl2 protein, mouseFibrinogen

Identifiers

PMID32133407
PMCPMC7043914
OpenAlexW3007122528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.