ArticleFrontiers in bioengineering and biotechnology2020
Intracellular Recording of Human Cardiac Action Potentials on Market-Available Multielectrode Array Platforms.
Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Morphology-modified contributions of electronic transitions to the optical response of plasmonic nanoporous gold metamaterial.Nature communications · 2026Article
- Nongenetic Photostimulation of hiPSC Neurons Using Plasmonic Nanopyramids.ACS photonics · 2025Article
- Non-invasive action potential recordings using printed electrolyte-gated polymer field-effect transistors.Nature communications · 2025Article
- Advanced passive 3D bioelectronics: powerful tool for the cardiac electrophysiology investigation.Microsystems & nanoengineering · 2025Review
- Effect of electrochemical topology on detection sensitivity in MEA assay for drug-induced cardiotoxicity screening.Biosensors & bioelectronics · 2025Article
- Electrode- and Label-Free Assessment of Electrophysiological Firing Rates through Cytochrome C Monitoring via Raman Spectroscopy.ACS sensors · 2025Article
- Organs-on-a-chip: a union of tissue engineering and microfabrication.Trends in biotechnology · 2023Review
- Cardiotoxicity drug screening based on whole-panel intracellular recording.Biosensors & bioelectronics · 2022Article
- Cellular and Engineered Organoids for Cardiovascular Models.Circulation research · 2022Review
- A biosensing system employing nanowell microelectrode arrays to record the intracellular potential of a single cardiomyocyte.Microsystems & nanoengineering · 2022Article
- All-Optical and Label-Free Stimulation of Action Potentials in Neurons and Cardiomyocytes by Plasmonic Porous Metamaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- Femtosecond Laser-Processing of Pre-Anodized Ti-Based Bone Implants for Cell-Repellent Functionalization.Nanomaterials (Basel, Switzerland) · 2021Article
- Intracellular action potential recordings from cardiomyocytes by ultrafast pulsed laser irradiation of fuzzy graphene microelectrodes.Science advances · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
High quality attenuated intracellular action potentials from large cell networks can be recorded on multi-electrode arrays by means of 3D vertical nanopillars using electrical pulses. However, most of the techniques require complex 3D nanostructures that prevent the straightforward translation into marketable products and the wide adoption in the scientific community. Moreover, 3D nanostructures are often delicate objects that cannot sustain several harsh use/cleaning cycles. On the contrary, laser optoacoustic poration allows the recording of action potentials on planar nanoporous electrodes made of noble metals. However, these constraints of the electrode material and morphology may also hinder the full exploitation of this methodology. Here, we show that optoacoustic poration is also very effective for porating cells on a large family of MEA electrode configurations, including robust electrodes made of nanoporous titanium nitride or disordered fractal-like gold nanostructures. This enables the recording of high quality cardiac action potentials in combination with optoacoustic poration, providing thus attenuated intracellular recordings on various already commercial devices used by a significant part of the research and industrial communities.
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