Evidence map›Paper›PMID 32133151›Full record

ArticleCell discovery2020

Structure and plasticity of silent synapses in developing hippocampal neurons visualized by super-resolution imaging.

Cheng Xu, Hui-Jing Liu, Lei Qi, Chang-Lu Tao, Yu-Jian Wang, Zeyu Shen, Chong-Li Tian, Pak-Ming Lau, Guo-Qiang Bi

Abstract read
In one paragraph

Article in Cell discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
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  7. Differential nanoscale organization of excitatory synapses onto excitatory vs. inhibitory neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Functional Inhibition of Katanin Affects Synaptic Plasticity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Serotonin Strengthens a Developing Glutamatergic Synapse through a PI3K-Dependent Mechanism.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Emergence of Neuronal Synchronisation in Coupled Areas.Frontiers in computational neuroscience · 2021
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cheng Xu *1Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230027 China.
Hui-Jing Liu *2School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027 China.
Lei Qi2School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027 China.
Chang-Lu Tao1Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230027 China.
Yu-Jian Wang1Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230027 China.
Zeyu Shen2School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027 China.
Chong-Li Tian2School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027 China.
Pak-Ming Lau2School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027 China.
Guo-Qiang Bi1Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230027 China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excitatory synapses in the mammalian brain exhibit diverse functional properties in transmission and plasticity. Directly visualizing the structural correlates of such functional heterogeneity is often hindered by the diffraction-limited resolution of conventional optical imaging techniques. Here, we used super-resolution stochastic optical reconstruction microscopy (STORM) to resolve structurally distinct excitatory synapses formed on dendritic shafts and spines. The majority of these shaft synapses contained

Indexed as

Membrane traffickingSuper-resolution microscopy

Identifiers

PMID32133151
PMCPMC7039918

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.