Evidence map›Paper›PMID 32132998›Full record

ArticleFrontiers in immunology2020

Goat Milk Consumption Enhances Innate and Adaptive Immunities and Alleviates Allergen-Induced Airway Inflammation in Offspring Mice.

Hui-Fang Kao, Yu-Chin Wang, Hsiu-Ying Tseng, Lawrence Shih-Hsin Wu, Hui-Ju Tsai, Miao-Hsi Hsieh, Pei-Chi Chen, Wen-Shou Kuo, Li-Fan Liu, Zhi-Gang Liu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Healthy Effects of Milk and Dairy Product Consumption in the Mediterranean Area and Japan.Endocrine, metabolic & immune disorders drug targets · 2024
    Review
  7. Article
  8. Article
  9. Biological Relevance of Goat Milk Oligosaccharides to Infant Health.Journal of agricultural and food chemistry · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Herbal Medicine, Gut Microbiota, and COVID-19.Frontiers in pharmacology · 2021
    Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Hui-Fang KaoDepartment of Nursing, National Tainan Junior College of Nursing, Tainan, Taiwan.
Yu-Chin WangCenter for Allergy and Clinical Immunology Research, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Hsiu-Ying TsengCenter for Allergy and Clinical Immunology Research, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Lawrence Shih-Hsin WuGraduate Institute of Medical Sciences, China Medical University, Taichung, Taiwan.
Hui-Ju TsaiDivision of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Miao-Hsi HsiehGraduate Institute of Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Pei-Chi ChenGraduate Institute of Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wen-Shou KuoCenter for Allergy and Clinical Immunology Research, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Li-Fan LiuInstitute of Gerontology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Zhi-Gang LiuDepartment of Respirology and Allergy, Third Affiliated Hospital of Shengzhen University, Shengzhen, China.
Jiu-Yao WangCenter for Allergy and Clinical Immunology Research, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
National Cheng Kung University · TWChina Medical University · TWNational Health Research Institutes · TWNational Tainan Institute of Nursing · TWPeking University Third Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Goat milk (GM), as compared to cow milk (CM), is easier for humans to digest. It also has antioxidant and anti-inflammatory effects and can improve minor digestive disorders and prevent allergic diseases in infants. It is unclear whether GM consumed in pregnant mothers has any protective effects on allergic diseases in infants. In this experimental study with mice, we found GM feeding enhanced immunoglobulin production, antigen-specific (ovalbumin, OVA) immune responses, and phagocytosis activity. The GM-fed mice had an increasing proportion of CD3

Indexed as

Adaptive ImmunityImmunity, InnateAllergensAnimalsAnimals, NewbornAsthmaDermatophagoides pteronyssinusDisease Models, AnimalFemaleGastrointestinal MicrobiomeGoatsMaleMiceMice, Inbred BALB CMilkOvalbuminAllergensOvalbuminallergic asthmagoat milkimmune responsemicrobiotapregnancy

Identifiers

PMID32132998
PMCPMC7040033
OpenAlexW3007883280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.