ArticleFrontiers in microbiology2020
A Novel Antidiabetic Monomers Combination Alleviates Insulin Resistance Through Bacteria-Cometabolism-Inflammation Responses.
Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Precision Microbiome Modulation: Exploring Lactobacillus spp. as A Targeted Strategy for Type 2 Diabetes Management.Current nutrition reports · 2026Review
- Paeoniflorin: a review of its pharmacology, pharmacokinetics and toxicity in diabetes.Frontiers in pharmacology · 2025Review
- Liver Metabolomics Analysis Revealing Key Metabolites Associated with Different Stages of Nonalcoholic Fatty Liver Disease in Hamsters.Combinatorial chemistry & high throughput screening · 2024Article
- Article
- Regulatory Effect of Mung Bean Peptide on Prediabetic Mice Induced by High-Fat Diet.Frontiers in nutrition · 2022Article
- Surrogate fostering of mice prevents prenatal estradiol-induced insulin resistanceFrontiers in microbiology · 2022Article
- Dysbiosis of intestinal microbiota in early life aggravates high-fat diet induced dysmetabolism in adult mice.BMC microbiology · 2021Article
- Dietary supplementation with Bacillus subtilis promotes growth performance of broilers by altering the dominant microbial community.Poultry science · 2021Article
- The Interaction between Mitochondrial Oxidative Stress and Gut Microbiota in the Cardiometabolic Consequences in Diet-Induced Obese Rats.Antioxidants (Basel, Switzerland) · 2020Article
- Alteration of Intestinal Microbiota in 3-Deoxyglucosone-Induced Prediabetic Rats.BioMed research international · 2020Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study sought to examine the therapeutic effect of a novel antidiabetic monomer combination (AMC) in treating type 2 diabetes mellitus (T2DM); while also elucidating the potential functional mechanism. Male C57BL/6J mice were fed a high-fat diet (HFD) for 12 weeks to establish T2DM. The AMC group showed significant reduction in weight, fasting blood glucose (FBG), serum total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C), and experienced reduced insulin resistance based on oral glucose tolerance testing (OGTT) and hyperinsulinemic-euglycemic clamp testing ("gold standard" for determining
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.