ArticleFrontiers in neurology2020
Primary Progressive Aphasia as a Prodromal State of Dementia With Lewy Bodies: A Case Report.
Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Minor Visual Phenomena in Lewy Body Disease: A Systematic Review.Biomedicines · 2025Review
- Aphasic mild cognitive impairment in prodromal dementia with Lewy bodies.Frontiers in neurology · 2023Article
- Neuropathological fingerprints of survival, atrophy and language in primary progressive aphasia.Brain : a journal of neurology · 2022Article
- Logogenic Primary Progressive Aphasia or Alzheimer Disease: Contribution of Acoustic Markers in Early Differential Diagnosis.Life (Basel, Switzerland) · 2022Article
- Unclassified fluent variants of primary progressive aphasia: distinction from semantic and logopenic variants.Brain communications · 2022Article
- Lewy Body Disease is a Contributor to Logopenic Progressive Aphasia Phenotype.Annals of neurology · 2021Article
- Data-Driven, Visual Framework for the Characterization of Aphasias Across Stroke, Post-resective, and Neurodegenerative Disorders Over Time.Frontiers in neurology · 2020Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dementia with Lewy bodies (DLB) is the second most common form of dementia in the elderly, and various clinical symptoms, including olfactory dysfunction, dysautonomia, depression, and rapid eye movement sleep behavior disorders (RBD), occur in patients with the prodromal state of DLB. We herein describe a case of a 72-years-old right-handed woman who exhibited primary progressive aphasia (PPA) as a prodromal state of DLB and took cholinesterase inhibitors (donepezil). At 4.5 years after aphasia onset, she exhibited all the core clinical features of DLB, including visual hallucinations, fluctuating cognition, RBD, and Parkinsonism, as well as progressive language impairment. She showed reduced dopamine transporter (DAT) uptake (assessed by DAT single-photon emission computed tomography imaging) in the striatum and decreased cardiac uptake (determined by
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