Evidence map›Paper›PMID 32132930›Full record

ArticleFrontiers in physiology2020

Topical Application of Wogonin Provides a Novel Treatment of Knee Osteoarthritis.

Jacob F Smith, Evan G Starr, Michael A Goodman, Romney B Hanson, Trent A Palmer, Jonathan B Woolstenhulme, Jeffery A Weyand, Andrew D Marchant, Shawen L Bueckers, Tanner K Nelson and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Veterinary sciences · 2025
    Review
  4. Flavonoids fromInternational journal of molecular sciences · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. The Use of Chinese Skullcap (Animals : an open access journal from MDPI · 2021
    Review
  10. Experimental Therapeutics for the Treatment of Osteoarthritis.Journal of experimental pharmacology · 2021
    Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Jacob F SmithDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Evan G StarrDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Michael A GoodmanDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Romney B HansonDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Trent A PalmerDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Jonathan B WoolstenhulmeDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Jeffery A WeyandDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Andrew D MarchantDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Shawen L BueckersDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Tanner K NelsonDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Matthew T SterlingDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Brandon J RoseDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
James P PorterDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Dennis L EggettStatistics, Brigham Young University, Provo, UT, United States.
David L KooymanDepartment of Physiology and Developmental Biology, Brigham Young University, Provo, UT, United States.
Brigham Young University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a degenerative joint disease characterized by inflammatory degradation of articular cartilage and subchondral bone. Wogonin, a compound extracted from the plant

Indexed as

HTRA1inflammationMMP-13NF-κBosteoarthritisTGF-β1wogonin

Identifiers

PMID32132930
PMCPMC7040489
OpenAlexW3006796061

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.