Evidence map›Paper›PMID 32132835›Full record

ArticleJournal of sports science & medicine2020

Changes in Urinary Titin N-terminal Fragment Concentration after Concentric and Eccentric Exercise.

Shota Yamaguchi, Katsuhiko Suzuki, Takayuki Inami, Kazue Kanda, Zhao Hanye, Junichi Okada

Abstract read
In one paragraph

Article in Journal of sports science & medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shota YamaguchiGraduate School of Sport Sciences, Waseda University, Saitama, Japan.
Katsuhiko SuzukiFaculty of Sport Sciences, Waseda University, Saitama, Japan.
Takayuki InamiInstitute of Physical Education, Keio University, Yokohama, Kanagawa, Japan.
Kazue KandaInstitute for Nanoscience & Nanotechnology, Waseda University, Shinjuku, Tokyo, Japan.
Zhao HanyeGraduate School of Sport Sciences, Waseda University, Saitama, Japan.
Junichi OkadaFaculty of Sport Sciences, Waseda University, Saitama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to compare the urinary titin N-terminal fragment (UTF) concentration after concentric and eccentric exercise and to clarify the specific response of UTF to exercise-induced muscle damage (EIMD). Nine healthy young men performed 30 concentric elbow flexion exercises with maximum effort, rested for at least eight weeks, and performed eccentric exercises at the same workload using the same arm. Changes in the maximal voluntary isometric contraction (MVIC), muscle soreness (SOR), range of motion (ROM), serum creatine kinase (CK) activity, and UTF concentrations were recorded before and after for six consecutive days after exercise. There was no significant difference in workload during exercise between the two exercise types. However, serum CK activity increased after eccentric exercise (p < 0.05). Additionally, MVIC, SOR, ROM, and UTF concentration were significantly higher after eccentric exercise than after concentric exercise (p < 0.05). Although workload was the same, the UTF concentration greatly increased after eccentric exercise. Based on these results, we suggest that UTF can be a non-invasive and highly specific biomarker of EIMD.

Indexed as

BiomarkersConnectinCreatine KinaseElbowExerciseHumansIsometric ContractionMaleMyalgiaRange of Motion, ArticularReproducibility of ResultsTime FactorsYoung AdultBiomarkersConnectinCreatine KinaseTTN protein, humanBiomarkerdelayed onset muscle sorenessexercise-induced muscle damagenon-inversivevalidity

Identifiers

PMID32132835
PMCPMC7039023

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.