Evidence map›Paper›PMID 32132713›Full record

ArticleNature2020

Olfactory receptor and circuit evolution promote host specialization.

Thomas O Auer, Mohammed A Khallaf, Ana F Silbering, Giovanna Zappia, Kaitlyn Ellis, Raquel Álvarez-Ocaña, J Roman Arguello, Bill S Hansson, Gregory S X E Jefferis, Sophie J C Caron and 2 more

Abstract readComparative Study
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 119 papers.

0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

119 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  6. Article
  7. Molecular bases of insect odorant receptor function: specificity and evolution.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  8. Convergent motifs of early olfactory processing are recapitulated by layer-wise efficient coding.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Receptor sequence divergence, gain, loss, duplication, and neofunctionalization drive olfactory adaptation inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Article
  11. Article
  12. Evolution of sensory systems underlies the emergence of predatory feeding behaviors in nematodes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

59 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Thomas O AuerCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. Thomas.Auer@unil.ch.
Mohammed A KhallafDepartment of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena, Germany.
Ana F SilberingCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Giovanna ZappiaCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Kaitlyn EllisDepartment of Biology, University of Utah, Salt Lake City, UT, USA.
Raquel Álvarez-OcañaCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
J Roman ArguelloDepartment of Ecology and Evolution, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Bill S HanssonDepartment of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena, Germany.
Gregory S X E JefferisDivision of Neurobiology, MRC Laboratory of Molecular Biology, Cambridge, UK.
Sophie J C CaronDepartment of Biology, University of Utah, Salt Lake City, UT, USA.
Markus KnadenDepartment of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena, Germany.
Richard BentonCenter for Integrative Genomics, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland. Richard.Benton@unil.ch.

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
DEVELOPMENTAL BIOLOGY TRAINING PROGRAMT32HD007491 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI James Alan Gagnon, Kristen M Kwan · 1995 to 2026
$8.0M
Biased randomness: a fundamental connectivity mechanism for associative brain centers.R01NS107970 · NINDS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Sophie Caron · 2018 to 2026
$3.0M
European Research Council 615094Medical Research Council MC_U105188491NICHD NIH HHS T32 HD007491NIH HHS P40 OD018537NINDS NIH HHS R01 NS107970Swiss National Science Foundation 166646
6 · The paper itself

Abstract

The evolution of animal behaviour is poorly understood

Indexed as

Host SpecificityMorindaAllelesAnimalsBehavior, AnimalBrainCalciumDrosophilaDrosophila melanogasterDrosophila ProteinsDrosophila simulansEvolution, MolecularFemaleFruitInterneuronsMaleCalciumDrosophila ProteinsOR22a protein, DrosophilaReceptors, Odorant

Identifiers

PMID32132713
PMCPMC7100913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.