Evidence map›Paper›PMID 32132651›Full record

ArticleOncogene2020

MNK1 signaling induces an ANGPTL4-mediated gene signature to drive melanoma progression.

William Yang, Elie Khoury, Qianyu Guo, Sathyen A Prabhu, Audrey Emond, Fan Huang, Christophe Gonçalves, Yao Zhan, Dany Plourde, Jessica N Nichol and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Oncogene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  4. Article
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  7. Article
  8. Identification ofComputational and structural biotechnology journal · 2023
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. The MNK1/2-eIF4E Axis as a Potential Therapeutic Target in Melanoma.International journal of molecular sciences · 2020
    Review
  14. Deeping in the Role of the MAP-Kinases Interacting Kinases (MNKs) in Cancer.International journal of molecular sciences · 2020
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

William Yang *Division of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Elie Khoury *Division of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Qianyu GuoDivision of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Sathyen A PrabhuDivision of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Audrey EmondLady Davis Institute, Jewish General Hospital, McGill University, Montréal, QC, Canada.ORCID http://orcid.org/0000-0001-8053-2784
Fan HuangDivision of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Christophe GonçalvesLady Davis Institute, Jewish General Hospital, McGill University, Montréal, QC, Canada.
Yao ZhanDivision of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Dany PlourdeLady Davis Institute, Jewish General Hospital, McGill University, Montréal, QC, Canada.
Jessica N NicholLady Davis Institute, Jewish General Hospital, McGill University, Montréal, QC, Canada.
Michael S DahabiehDivision of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada.
Wilson H Miller *Division of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada. wmiller@ldi.jgh.mcgill.ca.
Sonia Victoria Del Rincón *Division of Experimental Medicine, Faculty of Medicine, McGill University, Montréal, QC, Canada. sonia.delrincon@mcgill.ca.
Jewish General Hospital · CAMcGill University Health Centre · CA

Funding

Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) MOP-1422Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) MOP-142281Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) PJT-156269Gouvernement du Canada | Canadian Institutes of Health Research (Instituts de Recherche en Santé du Canada) PJT-162260
6 · The paper itself

Abstract

The BRAF

Indexed as

Angiopoietin-Like Protein 4AnimalsCell Line, TumorCutaneous Malignant MelanomaDisease ProgressionGene Expression Regulation, NeoplasticGene Knockout TechniquesHeterograftsHumansIntracellular Signaling Peptides and ProteinsLung NeoplasmsMelanomaMiceMutationNeoplasm InvasivenessProtein Kinase InhibitorsAngiopoietin-Like Protein 4ANGPTL4 protein, humanBRAF protein, humanIntracellular Signaling Peptides and ProteinsMKNK1 protein, humanProtein Kinase InhibitorsProtein Serine-Threonine KinasesProto-Oncogene Proteins B-raf

Identifiers

PMID32132651
OpenAlexW3010422213

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.