Evidence map›Paper›PMID 32132597›Full record

Trial reportScientific reports2020

Proteomic identification of early urinary-biomarkers of acute kidney injury in preterm infants.

Young Hwa Jung, Dohyun Han, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. New approaches to acute kidney injury.Clinical kidney journal · 2024
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Young Hwa JungDepartment of Pediatrics, Seoul National University College of Medicine, Seoul, South Korea.
Dohyun HanProteomics core facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, South Korea.
Seung Han ShinDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Ee-Kyung KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea.
Han-Suk KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, South Korea. kimhans@snu.ac.kr.
Seoul National University Children's Hospital · KRSeoul National University · KRSeoul National University Bundang Hospital · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immature preterm kidney is likely to be vulnerable to acute kidney injury (AKI). However, the biomarkers currently used for AKI are not sensitive or specific and are also inadequate for the timely detection of AKI in preterm infants. The objectives of this study were to identify novel urinary biomarkers of AKI using proteomic techniques, and to verify and validate that the candidates can serve as early predictive biomarkers for AKI. In total, 1,810 proteins were identified in the discovery phase. Among those proteins, 174 were selected as the 1

Indexed as

ProteomicsAcute Kidney InjuryAnnexin A5BiomarkersFemaleHumansInfantInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureLipocalin-2MaleS100 ProteinsAnnexin A5ANXA5 protein, humanBiomarkersLCN2 protein, humanLipocalin-2S100 Proteins

Identifiers

PMID32132597
PMCPMC7055268
OpenAlexW3009782853

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.