Evidence map›Paper›PMID 32132582›Full record

ArticleScientific reports2020

Retinal biomarkers and pharmacological targets for Hermansky-Pudlak syndrome 7.

Giovanni Luca Romano, Chiara Bianca Maria Platania, Gian Marco Leggio, Sebastiano Alfio Torrisi, Salvatore Giunta, Salvatore Salomone, Michele Purrello, Marco Ragusa, Cristina Barbagallo, Frank J Giblin and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Drug-Repurposing Strategy for Dimethyl Fumarate.Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Giovanni Luca Romano *Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, USA.
Chiara Bianca Maria Platania *
Gian Marco Leggio *Department of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Sebastiano Alfio TorrisiDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Salvatore GiuntaDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Salvatore SalomoneDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Michele PurrelloDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Marco RagusaDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Cristina BarbagalloDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.ORCID http://orcid.org/0000-0002-6769-4516
Frank J GiblinEye Research Institute, Oakland University, Rochester, Michigan, USA.
Rosa MastrogiacomoGenetics of Cognition Laboratory, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, Genova, Italy.
Francesca ManagòGenetics of Cognition Laboratory, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, Genova, Italy.ORCID http://orcid.org/0000-0003-3663-6193
Maurizio CammalleriDepartment of Biology, University of Pisa, Pisa, Italy.
Francesco PapaleoGenetics of Cognition Laboratory, Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, Genova, Italy.ORCID http://orcid.org/0000-0002-6326-0657
Filippo DragoDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy.
Claudio BucoloDepartment of Biomedical and Biotechnological Sciences, School of Medicine, University of Catania, Catania, Italy. claudio.bucolo@unict.it.
University of Catania · ITItalian Institute of Technology · ITOakland University · USUniversity of Miami · USUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deletion of dystrobrevin binding protein 1 has been linked to Hermansky-Pudlak syndrome type 7 (HPS-7), a rare disease characterized by oculocutaneous albinism and retinal dysfunction. We studied dysbindin-1 null mutant mice (Dys

Indexed as

Molecular Targeted TherapyAnimalsComputational BiologyGene Expression RegulationHermanski-Pudlak SyndromeMiceMice, Inbred C57BLMicroRNAsPrognosisRetinaMicroRNAs

Identifiers

PMID32132582
PMCPMC7055265
OpenAlexW3009671932

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.