Evidence map›Paper›PMID 32132578›Full record

ArticleScientific reports2020

Iron redox pathway revealed in ferritin via electron transfer analysis.

Peng Chen, Evelien De Meulenaere, Dimitri D Deheyn, Prabhakar R Bandaru

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Ferritin Single-Electron Transistor.The journal of physical chemistry. B · 2024
    Article
  7. Article
  8. Frontiers in veterinary science · 2023
    Article
  9. Effect of ultramarathon running on iron metabolism.Journal of the Chinese Medical Association : JCMA · 2023
    Article
  10. Article
  11. Conservative and Atypical Ferritins of Sponges.International journal of molecular sciences · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Peng ChenDepartment of Mechanical Engineering, University of California, San Diego, La Jolla, CA, 92093, USA.
Evelien De MeulenaereMarine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, 92037, USA.
Dimitri D Deheyn *Marine Biology Research Division, Scripps Institution of Oceanography, University of California, San Diego, La Jolla, CA, 92037, USA. ddeheyn@ucsd.edu.
Prabhakar R Bandaru *Department of Mechanical Engineering, University of California, San Diego, La Jolla, CA, 92093, USA. pbandaru@ucsd.edu.
University of California, San Diego · USScripps Institution of Oceanography · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferritin protein is involved in biological tissues in the storage and management of iron - an essential micro-nutrient in the majority of living systems. While there are extensive studies on iron-loaded ferritin, its functionality in iron delivery is not completely clear. Here, for the first time, differential pulse voltammetry (DPV) has been successfully adapted to address the challenge of resolving a cascade of fast and co-occurring redox steps in enzymatic systems such as ferritin. Using DPV, comparative analysis of ferritins from two evolutionary-distant organisms has allowed us to propose a stepwise resolution for the complex mix of concurrent redox steps that is inherent to ferritins and to fine-tune the structure-function relationship of each redox step. Indeed, the cyclic conversion between Fe

Identifiers

PMID32132578
PMCPMC7055317
OpenAlexW3009168386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.