ArticleScientific reports2020
Lactation stage impacts the glycolytic function of bovine CD4
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Metabolome analyses of the rumen, feces and blood reveal separate and simultaneous impacts of increased dietary concentrate and hindgut starch flow in Holstein cows.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- A single-cell transcriptomic study of milk cells from dairy cows with divergent lactation performance.Scientific reports · 2025Article
- Bioenergetic signatures of circulating blood cells as biosensors of metabolic health in food-producing animals.Frontiers in veterinary science · 2025Review
- Characterization of an in vitro model to study CD4JDS communications · 2024Article
- Immune cells phenotype and bioenergetic measures in CD4Scientific reports · 2024Article
- Preferential differential gene expression within the WC1.1Frontiers in immunology · 2023Article
- Synergistic Activation of Bovine CD4+ T Cells by Neutrophils and IL-12.Pathogens (Basel, Switzerland) · 2021Article
- Role of the JAK-STAT Pathway in Bovine Mastitis and Milk Production.Animals : an open access journal from MDPI · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dairy cattle undergo dynamic physiological changes over the course of a full lactation into the dry period, which impacts their immunocompetence. During activation, T cells undergo a characteristic rewiring to increase the uptake of glucose and metabolically reprogram to favor aerobic glycolysis over oxidative phosphorylation. To date it remains to be completely elucidated how the altered energetic demands associated with lactation in dairy cows impacts T cell metabolic reprogramming. Thus, in our ex vivo studies we have examined the influence of stage of lactation (early lactation into the dry period) on cellular metabolism in activated bovine CD4
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.