Evidence map›Paper›PMID 32132265›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Astrocytes Modulate Baroreflex Sensitivity at the Level of the Nucleus of the Solitary Tract.

Svetlana Mastitskaya, Egor Turovsky, Nephtali Marina, Shefeeq M Theparambil, Anna Hadjihambi, Sergey Kasparov, Anja G Teschemacher, Andrew G Ramage, Alexander V Gourine, Patrick S Hosford

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 31 citations in OpenAlex.

  1. Cholecystokinin Induces CaThe European journal of neuroscience · 2026
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  6. Glia of the heart's nervous system.Nature reviews. Neuroscience · 2025
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  20. The role of astrocytes in the nucleus tractus solitarii in maintaining central control of autonomic function.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Svetlana MastitskayaCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom.
Egor TurovskyInstitute of Cell Biophysics, Federal Research Center "Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences", Pushchino 142290, Russian Federation.
Nephtali MarinaCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom.
Shefeeq M TheparambilCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom.
Anna HadjihambiCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom.
Sergey KasparovPhysiology, Pharmacology, and Neuroscience, University of Bristol, Bristol BS8 1TD, United Kingdom.
Anja G TeschemacherPhysiology, Pharmacology, and Neuroscience, University of Bristol, Bristol BS8 1TD, United Kingdom.
Andrew G RamageCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom.
Alexander V GourineCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom, a.gourine@ucl.ac.uk p.hosford@qmul.ac.uk.
Patrick S HosfordCentre for Cardiovascular and Metabolic Neuroscience, Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom, a.gourine@ucl.ac.uk p.hosford@qmul.ac.uk.
University College London · GBUniversity of Bristol · GBInstitute of Cell Biophysics · RU

Funding

British Heart Foundation PG/13/79/30429British Heart Foundation PG/18/8/33540British Heart Foundation RG/14/4/30736British Heart Foundation RG/19/5/34463Wellcome Trust 095064Wellcome Trust 200893/Z/16/Z
6 · The paper itself

Abstract

Maintenance of cardiorespiratory homeostasis depends on autonomic reflexes controlled by neuronal circuits of the brainstem. The neurophysiology and neuroanatomy of these reflex pathways are well understood, however, the mechanisms and functional significance of autonomic circuit modulation by glial cells remain largely unknown. In the experiments conducted in male laboratory rats we show that astrocytes of the nucleus of the solitary tract (NTS), the brain area that receives and integrates sensory information from the heart and blood vessels, respond to incoming afferent inputs with [Ca

Indexed as

Adenosine TriphosphateAnimalsAstrocytesBaroreflexCalcium SignalingMaleNeurons, AfferentNeurotransmitter AgentsPurinergic P2Y Receptor AgonistsPurinergic P2Y Receptor AntagonistsRatsRats, Sprague-DawleyReceptors, AMPAReceptor, Serotonin, 5-HT2AReceptors, Purinergic P2Y1SerotoninAdenosine TriphosphateNeurotransmitter AgentsPurinergic P2Y Receptor AgonistsPurinergic P2Y Receptor AntagonistsReceptors, AMPAReceptor, Serotonin, 5-HT2AReceptors, Purinergic P2Y1SerotoninSNARE Proteinsastrocytesbaroreflexcardiovascularin vivonucleus of the solitary tractviral gene transfer

Identifiers

PMID32132265
PMCPMC7141885
OpenAlexW3010502640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.