Evidence map›Paper›PMID 32132169›Full record

ArticleG3 (Bethesda, Md.)2020

A

Cristina Aguirre-Chen, Natalia Stec, Olivia Mendivil Ramos, Nuri Kim, Melissa Kramer, Shane McCarthy, Jesse Gillis, W Richard McCombie, Christopher M Hammell

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Antioxidants, Hormetic Nutrition, and Autism.Current neuropharmacology · 2024
    Review
  7. Article
  8. Review
  9. Review
  10. Ankyrins and neurological disease.Current opinion in neurobiology · 2021
    Review
  11. Article
  12. Article
  13. Homeostatic Roles of the Proteostasis Network in Dendrites.Frontiers in cellular neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Cristina Aguirre-ChenCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.
Natalia StecCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.
Olivia Mendivil RamosCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.ORCID 0000-0003-3740-1943
Nuri KimCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.
Melissa KramerCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.
Shane McCarthyCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.
Jesse GillisCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.
W Richard McCombieCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724.
Christopher M HammellCold Spring Harbor Laboratory, One Bungtown Road, Cold Spring Harbor, NY 11724 chammell@cshl.edu.ORCID 0000-0002-5961-0976
Cold Spring Harbor Laboratory · US

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI John Edward Moses · 1987 to 2026
$118.9M
OSCILLATORY GENE EXPRESSION AND THE MAINTENANCE OF TEMPORAL PATTERNINGR01GM117406 · NIGMS · COLD SPRING HARBOR LABORATORY · PI HAMMELL, CHRISTOPHER MARTIN · 2016 to 2025
$4.0M
Revealing the transcriptomic basis of neuronal identity through functional meta-analysisR01MH113005 · NIMH · COLD SPRING HARBOR LABORATORY · PI GILLIS, JESSE · 2017 to 2021
$2.4M
Heuristics to evaluate biomedical and genomic knowledge bases for validityR01LM012736 · NLM · COLD SPRING HARBOR LABORATORY · PI GILLIS, JESSE · 2017 to 2020
$1.9M
NCI NIH HHS P30 CA045508NIGMS NIH HHS R01 GM117406NIMH NIH HHS R01 MH113005NLM NIH HHS R01 LM012736
6 · The paper itself

Abstract

Analysis of patient-derived DNA samples has identified hundreds of variants that are likely involved in neuropsychiatric diseases such as autism spectrum disorder (ASD) and schizophrenia (SCZ). While these studies couple behavioral phenotypes to individual genotypes, the number and diversity of candidate genes implicated in these disorders highlights the fact that the mechanistic underpinnings of these disorders are largely unknown. Here, we describe a RNAi-based screening platform that uses

Indexed as

Autism Spectrum DisorderCaenorhabditis elegans ProteinsAnimalsCaenorhabditis elegansHumansRNA InterferenceTranscription FactorsCaenorhabditis elegans ProteinsTranscription Factorsautism spectrum disorderCaenorhabditis elegansdendritic arborizationmodel organismneuronal developmentneuropsychiatric risk genesRNA interferenceschizophrenia

Identifiers

PMID32132169
PMCPMC7202017
OpenAlexW3010555113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.