ArticleGenome research2020
An integrative view of the regulatory and transcriptional landscapes in mouse hematopoiesis.
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Article in Genome research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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33citing papers in PubMed
–field-weighted citation impact
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Who cites it
33 citing papers in PubMed, 78 citations in OpenAlex.
- Integrative Epigenomics: Bioinformatics Strategies for Multi-Omics Data Analysis in Health and Disease.Epigenomes · 2026Review
- Pan-cell type continuous chromatin state annotation of 1,698 epigenomes from the International Human Epigenome Consortium.Genome biology · 2026Article
- Predictive modeling of signal-responsive cis-elements in human red blood cell precursors.Nucleic acids research · 2026Article
- Chromatin reorganization drives overexpression of a Btaf1 variant underpinning hematopoietic aging.Nature communications · 2026Article
- Mechanisms of Globin Gene Regulation in Mammals.Annual review of genetics · 2025Review
- Regeneration alters open chromatin andGenome research · 2025Article
- In vivo deletion of a GWAS-identified Myb distal enhancer acts on Myb expression, globin switching, and clinical erythroid parameters in β-thalassemia.Scientific reports · 2025Article
- Unlocking hematopoietic stem cell potential: integrative computational approaches for genomic and transcriptomic analysis.Frontiers in cell and developmental biology · 2025Review
- Erythropoiesis: insights from a genomic perspective.Experimental & molecular medicine · 2024Review
- Activating mutations remodel the chromatin accessibility landscape to drive distinct regulatory networks inHemaSphere · 2024Article
- Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes.Genome research · 2024Article
- Parallel Evolution at the Regulatory Base-Pair Level Contributes to Mammalian Interspecific Differences in Polygenic Traits.Molecular biology and evolution · 2024Article
- Interpretable prediction of mRNA abundance from promoter sequence using contextual regression models.NAR genomics and bioinformatics · 2024Article
- CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex.Cell reports · 2024Article
- JMnorm: a novel joint multi-feature normalization method for integrative and comparative epigenomics.Nucleic acids research · 2024Article
- Inferring chromatin accessibility during murine hematopoiesis through phylogenetic analysis.BMC research notes · 2023Article
- An NFIX-mediated regulatory network governs the balance of hematopoietic stem and progenitor cells during hematopoiesis.Blood advances · 2023Article
- Predicting the impact of sequence motifs on gene regulation using single-cell data.Genome biology · 2023Article
- AdaLiftOver: high-resolution identification of orthologous regulatory elements with Adaptive liftOver.Bioinformatics (Oxford, England) · 2023Article
- Snapshot: a package for clustering and visualizing epigenetic history during cell differentiation.BMC bioinformatics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 7 institutions in 2 countries.
Guanjue Xiang *Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0003-1328-7197
Cheryl A Keller *Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0001-6594-0245
Elisabeth HeustonNHGRI Hematopoiesis Section, Genetics and Molecular Biology Branch, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000-0002-1603-4083
Belinda M GiardineDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-4681-1074
Lin AnDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-8313-0796
Alexander Q WixomDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0003-2982-7303
Amber MillerDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
April CockburnDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Michael E G SauriaDepartments of Biology and Computer Science, Johns Hopkins University, Baltimore, Maryland 20218, USA.ORCID 0000-0001-5556-9446
Kathryn WeaverDepartments of Biology and Computer Science, Johns Hopkins University, Baltimore, Maryland 20218, USA.
Jens LichtenbergNHGRI Hematopoiesis Section, Genetics and Molecular Biology Branch, National Institutes of Health, Bethesda, Maryland 20892, USA.ORCID 0000-0002-0023-4937
Berthold GöttgensWelcome and MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge CB2 1TN, United Kingdom.ORCID 0000-0001-6302-5705
Qunhua LiDepartment of Statistics, Program in Bioinformatics and Genomics, Center for Computational Biology and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
David BodineNHGRI Hematopoiesis Section, Genetics and Molecular Biology Branch, National Institutes of Health, Bethesda, Maryland 20892, USA.
Shaun MahonyDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0002-2641-1807
James TaylorDepartments of Biology and Computer Science, Johns Hopkins University, Baltimore, Maryland 20218, USA.ORCID 0000-0001-5079-840X
Gerd A BlobelDepartment of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.ORCID 0000-0002-0714-9612
Mitchell J WeissDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.ORCID 0000-0003-2460-3036
Yong ChengDepartment of Hematology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.ORCID 0000-0002-9314-0971
Feng YueDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, USA.ORCID 0000-0002-7954-5462
Jim HughesMRC Weatherall Institute of Molecular Medicine, Oxford University, Oxford OX3 9DS, United Kingdom.ORCID 0000-0002-8955-7256
Douglas R HiggsMRC Weatherall Institute of Molecular Medicine, Oxford University, Oxford OX3 9DS, United Kingdom.ORCID 0000-0003-3579-8705
Yu ZhangDepartment of Statistics, Program in Bioinformatics and Genomics, Center for Computational Biology and Bioinformatics, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.
Ross C HardisonDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.ORCID 0000-0003-4084-7516
Pennsylvania State University · USJohns Hopkins University · USNational Institutes of Health · USSt. Jude Children's Research Hospital · USUniversity of Oxford · GBChildren's Hospital of Philadelphia · USWellcome/MRC Cambridge Stem Cell Institute · GB
Funding
Toward a comprehensive functional annotation of the human genomeU54HG006998 · NHGRI · HUDSON-ALPHA INSTITUTE FOR BIOTECHNOLOGY · PI MYERS, RICHARD M · 2012 to 2016
$17.5MHematopoietic Stem Cell BiologyZIAHG000083 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BODINE, DAVID M. · 2009 to 2022
$12.1MVISION: ValIdated Systematic IntegratiON of epigenomic dataR24DK106766 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI BLOBEL, GERD A, BODINE, DAVID M. · 2016 to 2020
$6.2MImpact of genetic variants on gene regulation and 3D genome organization in human diseasesR35GM124820 · NIGMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Feng Yue · 2017 to 2026
$4.0MVisualization, modeling and validation of chromatin interaction dataR01HG009906 · NHGRI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI YUE, FENG · 2018 to 2022
$2.0MMedical Research Council G1000801Medical Research Council MC_PC_12009Medical Research Council MC_PC_15069Medical Research Council MC_PC_17230Medical Research Council MC_U137961144Medical Research Council MC_U137961145Medical Research Council MC_UU_00016/12Medical Research Council MC_UU_00016/4Medical Research Council MC_UU_12009/13Medical Research Council MC_UU_12009/4Medical Research Council MR/M008975/1NHGRI NIH HHS R01 HG009906NHGRI NIH HHS U54 HG006998NIDDK NIH HHS R24 DK106766
Abstract
Thousands of epigenomic data sets have been generated in the past decade, but it is difficult for researchers to effectively use all the data relevant to their projects. Systematic integrative analysis can help meet this need, and the VISION project was established for
Indexed as
Epigenesis, GeneticAnimalsHematopoiesisHematopoietic Stem CellsMiceRegulatory Elements, TranscriptionalTranscriptome
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