Evidence map›Paper›PMID 32131887›Full record

ArticleBMC research notes2020

A comparison of three column agglutination tests for red blood cell alloantibody identification.

Siska Blomme, Emilie De Maertelaere, Eline Verhoye

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Siska BlommeClinical Department of Laboratory Medicine, University Hospitals, Herestraat, 49 3000, Leuven, Belgium. blommesiska@gmail.com.
Emilie De MaertelaereClinical Department of Laboratory Medicine, University Hospitals, St. Pietersnieuwstraat 33, 9000, Ghent, Belgium.
Eline VerhoyeClinical Departments of Laboratory Medicine, AZ Delta Hospital, Ardooisesteenweg 276, 8800, Roeselare, Belgium.
AZ Delta · BEGhent University Hospital · BEKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCommercial kits of column tests for pre-transfusion testing have progressively replaced conventional tube tests in most laboratories. Aim of this study was to compare three commercial test cell panels for the identification of irregular red blood cell (RBC) alloantibodies. Overall, 44 samples with a positive indirect antiglobulin test (IAT) by routine testing were used for comparison of following panels: Ortho RESOLVE

resultsAlloantibody identification was possible in 38 samples, of which identical identification was shown in 33 samples by all methods. The remaining samples showed differences between certain methods, with the gel card system being superior to the glass card system for analyzing stored samples Considering that not all samples were evaluated in all three methods, the concordance rate reached 100% between Bio-Rad and Grifols, 90.5% between Bio-Rad and OCD, 86.5% between OCD and Grifols and 90.5% between all methods. Although differences in sensitivities were seen for specific antibodies, the three methods showed comparable performance for the identification of RBC alloantibodies.

Indexed as

Agglutination TestsBlood Grouping and CrossmatchingErythrocytesHumansIsoantibodiesReagent Kits, DiagnosticSensitivity and SpecificityTransfusion MedicineIsoantibodiesReagent Kits, DiagnosticAlloantibody identificationColumn agglutination techniquePre-transfusion testingRed blood cell antibodiesTransfusion medicine

Identifiers

PMID32131887
PMCPMC7057655
OpenAlexW3011285564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.