ArticleBMC microbiology2020
Tracing cross species transmission of Mycobacterium bovis at the wildlife/livestock interface in South Africa.
Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Methods for Detecting Mycobacterial Mixed Strain Infections-A Systematic Review.Frontiers in genetics · 2020Pooled it
- The Global Prevalence of Tuberculosis Infection in Buffaloes: A Systematic Review and Meta-Analysis.Animals : an open access journal from MDPI · 2026Review
- Animal Welfare, Carcass-Processing Practices and Post-Mortem Lesions in Nigerian Municipal Slaughterhouses: Implications for Meat Quality and Public Health Security.Veterinary sciences · 2026Article
- Whole-genome sequencing reveals genetic diversity and transmission dynamics ofMicrobial genomics · 2026Article
- Prevalence and Risk Factors of Tuberculosis Lesions in Cattle Slaughtered for Human Consumption at the Slaughterhouses in the City of Ngaoundéré, Cameroon.Veterinary medicine international · 2026Article
- Isolation of viable Mycobacterium bovis from faeces of naturally infected free-ranging rural domestic cattle (Bos taurus).Journal of applied microbiology · 2025Article
- Generalizing an outbreak cluster detection method for two groups: an application to rabies.Royal Society open science · 2025Article
- Identification and molecular characterization ofOne health (Amsterdam, Netherlands) · 2024Article
- Genomic insights into anthropozoonotic tuberculosis in captive sun bears (Helarctos malayanus) and an Asiatic black bear (Ursus thibetanus) in Cambodia.Scientific reports · 2024Article
- Whole genome sequencing improves the discrimination betweenOne health (Amsterdam, Netherlands) · 2023Article
- Review
- Challenges to the control of Mycobacterium bovis in livestock and wildlife populations in the South African context.Irish veterinary journal · 2023Article
- Bovine brucellosis and tuberculosis at a livestock-wildlife interface in Zimbabwe: A nexus for amplification of a zoonosis or a myth?Veterinary medicine and science · 2023Article
- Evidence, Challenges, and Knowledge Gaps Regarding Latent Tuberculosis in Animals.Microorganisms · 2022Review
- The Potential Risk of International Spread ofJournal of veterinary research · 2022Article
- Molecular characterization ofIranian journal of veterinary research · 2022Article
- Review of Diagnostic Tests for Detection ofFrontiers in veterinary science · 2021Review
- Bovine Tuberculosis: The Emergence of a New Wildlife Maintenance Host in Ireland.Frontiers in veterinary science · 2021Article
- Review
- Epidemiology of Tuberculosis in Multi-Host Wildlife Systems: Implications for Black (Frontiers in veterinary science · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
Abstract
backgroundBovine tuberculosis (bTB) affects cattle and wildlife in South Africa with the African buffalo (Syncerus caffer) as the principal maintenance host. The presence of a wildlife maintenance host at the wildlife/livestock interface acting as spill-over host makes it much more challenging to control and eradicate bTB in cattle. Spoligotyping and mycobacterial interspersed repetitive unit-variable number of tandem repeat (MIRU-VNTR) genotyping methods were performed to investigate the genetic diversity of Mycobacterium bovis (M. bovis) isolates from cattle and wildlife, their distribution and transmission at the wildlife/livestock interface in northern Kwa-Zulu Natal (KZN), South Africa.
resultsSB0130 was identified as the dominant spoligotype pattern at this wildlife/livestock interface, while VNTR typing revealed a total of 29 VNTR profiles (strains) in the KZN province signifying high genetic variability. The detection of 5 VNTR profiles shared between cattle and buffalo suggests M. bovis transmission between species. MIRU-VNTR confirmed co-infection in one cow with three strains of M. bovis that differed at a single locus, with 2 being shared with buffalo, implying pathogen introduction from most probably unrelated wildlife sources.
conclusionOur findings highlight inter and intra species transmission of bTB at the wildlife/livestock interface and the need for the implementation of adequate bTB control measures to mitigate the spread of the pathogen responsible for economic losses and a public health threat.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.