Evidence map›Paper›PMID 32131612›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2020

B Lymphocytes and Adipose Tissue Inflammation.

Prasad Srikakulapu, Coleen A McNamara

Open access · bronzeAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Influence of Weight Loss and Weight Regain on Adipose Tissue Inflammation.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Prasad SrikakulapuFrom the Cardiovascular Research Center, Cardiovascular Division, Department of Medicine, University of Virginia, Charlottesville.
Coleen A McNamaraFrom the Cardiovascular Research Center, Cardiovascular Division, Department of Medicine, University of Virginia, Charlottesville.
University of Virginia · US

Funding

ROLE OF LIPOXYGENASES IN ATHEROGENESIS IN DIABETES MELLITUSP01HL055798 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI TAYLOR, ANGELA M · 1995 to 2016
$28.4M
Project 4: APOB-specific CD4 and CD8 T cells exacerbate atherosclerosisP01HL136275 · NHLBI · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI Catherine C Hedrick · 2017 to 2026
$25.5M
Local B-1 Regulation of AtherosclerosisR01HL136098 · NHLBI · UNIVERSITY OF VIRGINIA · PI MCNAMARA, COLEEN A · 2017 to 2020
$3.1M
Genetic Regulation of B Lymphocyte Aortic Homing and AtheroprotectionR01HL107490 · NHLBI · UNIVERSITY OF VIRGINIA · PI MCNAMARA, COLEEN A · 2011 to 2014
$1.5M
Id3/B Lymphocytes and AtherosclerosisR01HL096447 · NHLBI · UNIVERSITY OF VIRGINIA · PI MCNAMARA, COLEEN A · 2009 to 2010
$1.0M
NHLBI NIH HHS P01 HL055798NHLBI NIH HHS P01 HL136275NHLBI NIH HHS R01 HL096447NHLBI NIH HHS R01 HL107490NHLBI NIH HHS R01 HL136098
6 · The paper itself

Abstract

The immune system plays an important role in obesity-induced adipose tissue inflammation and the resultant metabolic dysfunction, which can lead to hypertension, dyslipidemia, and insulin resistance and their downstream sequelae of type 2 diabetes mellitus and cardiovascular disease. While macrophages are the most abundant immune cell type in adipose tissue, other immune cells are also present, such as B cells, which play important roles in regulating adipose tissue inflammation. This brief review will overview B-cell subsets, describe their localization in various adipose depots and summarize our knowledge about the function of these B-cell subsets in regulating adipose tissue inflammation, obesity-induced metabolic dysfunction and atherosclerosis.

Indexed as

Adipose TissueAnimalsAnti-Inflammatory AgentsAtherosclerosisAutoimmunityB-Lymphocyte SubsetsCell CommunicationCytokinesHumansImmunotherapyInflammation MediatorsPanniculitisPhenotypeSignal TransductionAnti-Inflammatory AgentsCytokinesInflammation Mediatorsadipose tissueatherosclerosisB cellsinflammationinsulin resistanceobesity

Identifiers

PMID32131612
PMCPMC7398177
OpenAlexW3010149894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.