ArticlePolymers2020
Exploring NIR Aza-BODIPY-Based Polarity Sensitive Probes with ON-and-OFF Fluorescence Switching in Pluronic Nanoparticles.
Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Improving the spatial resolution and signal-to-noise ratio of ultrasound switchable fluorescence imaging.Journal of biophotonics · 2024Article
- Ultrasound-switchable fluorescence thermometry with dual detection channels using temperature-sensitive liposomes.Journal of biophotonics · 2024Article
- Non-destructive real-time monitoring and investigation of the self-assembly process using fluorescent probes.Chemical science · 2024Review
- Substituent directed cellular imaging in the 800-850 nm range with BFRSC advances · 2023Article
- Exploiting directed self-assembly and disassembly for off-to-on fluorescence responsive live cell imaging.RSC advances · 2022Review
- Solvent-Dependent Fluorescence Properties of CHInternational journal of molecular sciences · 2022Article
- Thermo- and pH-sensitive nanoparticles of poly (Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Fluorescent Polymers Conspectus.Polymers · 2022Review
- Near-infrared temperature-switchable fluorescence nanoparticles.Quantitative imaging in medicine and surgery · 2021Article
- The Magical Combination of Polymer Science and Fluorometry.Polymers · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Because of their deep penetration capability in tissue, red or near infrared (NIR) fluorophores attract much attention in bio-optical imaging. Among these fluorophores, the ones that respond to the immediate microenvironment (i.e., temperature, polarity, pH, viscosity, hypoxia, etc.) are highly desirable. We studied the response of six NIR aza-BODIPY-based and structurally similar fluorophores to polarity and viscosity for incorporation inside Pluronic nanoparticles as switchable fluorescent probes (SFPs). Based on our results, all of these fluorophores were moderately to strongly sensitive to the polarity of the microenvironment. We concluded that attaching amine groups to the fluorophore is not necessary for having strong polarity sensitive probes. We further studied the response of the fluorophores when embedded inside Pluronic nanoparticles and found that four of them qualified as SFPs. We also found that the switching ratio of the fluorophore-encapsulated Pluronic nanoparticles (I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.