Evidence map›Paper›PMID 32130787›Full record

ArticleJournal of cellular and molecular medicine2020

iNOS-inhibitor driven neuroprotection in a porcine retina organ culture model.

José Hurst, Ana Maria Mueller-Buehl, Lisa Hofmann, Sandra Kuehn, Fenja Herms, Sven Schnichels, Stephanie Christine Joachim

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  16. Organ Cultures for Retinal Diseases.Frontiers in neuroscience · 2020
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

José HurstCentre for Ophthalmology Tübingen, University Eye Hospital, Tübingen, Germany.ORCID 0000-0002-8697-2569
Ana Maria Mueller-BuehlExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, Bochum, Germany.
Lisa HofmannExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, Bochum, Germany.
Sandra KuehnExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, Bochum, Germany.
Fenja HermsExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, Bochum, Germany.
Sven SchnichelsCentre for Ophthalmology Tübingen, University Eye Hospital, Tübingen, Germany.ORCID 0000-0002-2385-5517
Stephanie Christine JoachimExperimental Eye Research Institute, University Eye Hospital, Ruhr-University Bochum, Bochum, Germany.ORCID 0000-0001-7056-0829
University Hospitals of the Ruhr-University of Bochum · DESTZ eyetrial · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrite oxide plays an important role in the pathogenesis of various retinal diseases, especially when hypoxic processes are involved. This degeneration can be simulated by incubating porcine retinal explants with CoCl

Indexed as

Amacrine CellsAmidinesAnimalsApoptosisBenzylaminesCell HypoxiaDisease Models, AnimalHumansMicrogliaNeuroprotectionNeuroprotective AgentsNitric Oxide Synthase Type IIOrgan Culture TechniquesRetinaRetinal DiseasesRetinal Ganglion CellsAmidinesBenzylaminesN-(3-(aminomethyl)benzyl)acetamidineNeuroprotective AgentsNitric Oxide Synthase Type IIhypoxiaiNOS-inhibitor 1400Worgan cultureretinaretinal ganglion cells

Identifiers

PMID32130787
PMCPMC7171393
OpenAlexW3009823515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.