SynthesisThoracic cancer2020
The value of navigation bronchoscopy in the diagnosis of peripheral pulmonary lesions: A meta-analysis.
Synthesis in Thoracic cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Robotic-assisted bronchoscopy for the diagnosis of peripheral pulmonary lesions: A systematic review and meta-analysis.Thoracic cancer · 2024Pooled it
- Virtual bronchoscopic navigationTherapeutic advances in respiratory diseasePooled it
- Ultrathin bronchoscope combined with virtual bronchoscopic navigation and endobronchial ultrasound for the diagnosis of peripheral pulmonary lesions with or without fluoroscopy: A randomized trial.Thoracic cancer · 2021Trial
- 3D computed tomography airway geometry for predicting bronchoscopic accessibility in peripheral pulmonary nodules: a prospective study.Translational lung cancer research · 2026Article
- Meta-analysis of the changes in clinical features and characteristics of lung cancer under bronchoscopy.American journal of clinical and experimental immunology · 2026Article
- Bronchoscopic Strategies to Improve Diagnostic Yield in Pulmonary Tuberculosis Patients.Tuberculosis and respiratory diseases · 2024Article
- Novel diagnostic processes and challenges in bronchoscopy.Pathology oncology research : POR · 2024Review
- Cone-Beam Computed Tomography-Guided Cryobiopsy Combined with Conventional Biopsy for Ground Glass Opacity-Predominant Pulmonary Nodules.Respiration; international review of thoracic diseases · 2024Article
- Non‑diagnostic electromagnetic navigation bronchoscopy biopsy: Predictive factors and final diagnoses.Oncology letters · 2023Article
- Thoracic surgery in Hong Kong.Journal of thoracic disease · 2022Review
- Real-World Diagnostic Accuracy and Use of Immunohistochemical Markers in Lung Cancer Diagnostics.Biomolecules · 2021Article
- Advances in Diagnostic Bronchoscopy.Diagnostics (Basel, Switzerland) · 2021Review
- Observational
- Augmented fluoroscopy and cone beam CT-guided needle biopsy using a steerable guiding sheath: a promising approach for peripheral pulmonary lesions.Translational lung cancer research · 2021Article
- The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy.Thoracic cancer · 2021Article
- Diagnostic yield and safety of biopsy guided by electromagnetic navigation bronchoscopy for high-risk pulmonary nodules.Thoracic cancer · 2021Article
- Chinese expert consensus on technical specifications of electromagnetic navigation bronchoscopy in diagnosing peripheral pulmonary lesions.Journal of thoracic disease · 2021Review
- Virtual bronchoscopic navigation without fluoroscopy guidance for peripheral pulmonary lesions in inexperienced pulmonologist.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTo compare the diagnostic yield of peripheral pulmonary lesions (PPLs) with and without navigation system.
methodsStudies dating from January 1990 to October 2019 were collected from databases. Diagnostic yield of navigation bronchoscopy and non-navigation bronchoscopy was extracted from comparative studies. Subgroup analysis was adopted to test diagnostic yield variation by lesion size, lobe location of the lesion, distance from the hilum, bronchus sign and nature of the lesion.
resultsIn total, 2131 patients from 10 studies were enrolled into the study. Diagnostic yield of navigation bronchoscopy was statistically higher than non-navigation bronchoscopy for PPLs (odds ratio [OR] 1.69, 95% confidence interval [CI] 1.32, 2.18, P < 0.001), particularly for PPLs in the peripheral third lung (OR 2.26, 95% CI 1.48, 3.44, P < 0.001) and for bronchus sign positive PPLs (OR 2.26, 95% CI 1.21, 4.26, P = 0.011). Navigation bronchoscopy had better performance than non-navigation bronchoscopy when PPLs were ≤ 20 mm (OR 2.09, 95% CI 1.44, 3.03, P < 0.001). It also elevated diagnostic yield of malignant PPLs (OR 1.67, 95% CI 1.26, 2.22, P < 0.001) and PPLs in the bilateral upper lobes (OR 1.50, 95% CI 1.09, 2.08, P = 0.014).
conclusionsNavigation bronchoscopy enhanced diagnostic yield when compared to non-navigation bronchoscopy, particularly for PPLs in the peripheral third lung, PPLs being bronchus sign positive, PPLs ≤ 20 mm, malignant PPLs and PPLs in the bilateral upper lobes. KEY POINTS: The current study provided systematic evaluation on the diagnostic value of navigation bronchoscopy by comparing it with non-navigation bronchoscopy, and exploring the factors affecting the diagnostic yield.
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