Evidence map›Paper›PMID 32130757›Full record

Trial reportEuropean eating disorders review : the journal of the Eating Disorders Association2020

Remission in adolescents with bulimia nervosa: Empirical evaluation of current conceptual models.

Sasha Gorrell, Brittany E Matheson, James Lock, Daniel Le Grange

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European eating disorders review : the journal of the Eating Disorders Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06213883 (Characterizing Acute Exercise Response in Restrictive Eating Disorders), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06213883 nacompletednot on this mapstarted 2023, after this paper: background citation

Characterizing Acute Exercise Response in Restrictive Eating Disorders

TypeinterventionalSponsorUniversity of Wisconsin, MadisonRan2023 to 2025Enrolled74ConditionsEating DisordersArmsBiobehavioral Response to in-lab exposure to physical activity
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Defining Recovery and Relapse in Bulimia Nervosa: A Systematic Review of the Literature.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Pooled it
  2. Neurocognitive Profiles and Predictors of Symptom Trajectory During and After Treatment in Adolescent Bulimia Nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Trial
  3. Trial
  4. Trial
  5. Weight Suppression, Brain Reward Response to Food Cues, and Bulimic Behaviours: A Pilot fMRI Study.European eating disorders review : the journal of the Eating Disorders Association · 2026
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sasha GorrellDepartment of Psychiatry, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-8861-8547
Brittany E MathesonDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.
James LockDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.ORCID 0000-0002-5169-1484
Daniel Le GrangeDepartment of Psychiatry, University of California, San Francisco, San Francisco, California, USA.
Stanford University · USUniversity of California, San Francisco · US

Funding

CLINICAL SERVICES RESEARCH TRAINING PROGRAMT32MH018261 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Kaja Zabrina LeWinn, Rachel L. Loewy · 1985 to 2026
$7.0M
1/2-Treatment of Bulimic AdolescentsR01MH079978 · NIMH · STANFORD UNIVERSITY · PI LOCK, JAMES D · 2008 to 2012
$2.2M
2/2 Predictors and Course of Postpartum Obsessions and CompulsionsR01MH118261 · NIMH · JOHNS HOPKINS UNIVERSITY · PI NESTADT, GERALD · 2019 to 2023
$2.1M
2/2-Treatment of Adolescent BulimicsR01MH079979 · NIMH · UNIVERSITY OF CHICAGO · PI LE GRANGE, DANIEL · 2008 to 2012
$1.5M
NIMH NIH HHS R01 MH079978NIMH NIH HHS R01 MH079979NIMH NIH HHS R01 MH118261NIMH NIH HHS T32 MH018261
6 · The paper itself

Abstract

objectiveThe few randomized clinical trials (RCTs) investigating adolescent treatment for bulimia nervosa (BN) suggest variability in both rates of, and criteria for remission. The current study examined reactivity in remission rates, relative to various conceptualizations of remission in a single RCT data set.

methodA data set of adolescents with BN who participated in an RCT (N = 110) was used to evaluate remission models based upon behavioral symptoms (e.g., binge eating), psychological symptoms (Eating Disorder Examination [EDE] scores), and combinations of these criteria.

resultsAt end-of-treatment (EOT), a remission model defined by behavioral symptom abstinence plus meaningful reduction in EDE global scores yielded comparable remission rates to a model defined by behavioral abstinence alone (i.e., 29% remitted). Participants with higher EOT EDE global scores were less likely to be abstinent from behavioral symptoms at 6- and 12-month follow-up (ps < .001). DISCUSSION: Reduction in psychological symptoms with behavioral abstinence did not inform remission status at EOT, over and above behavioral symptom change alone. However, psychological symptom improvement by EOT may predict positive prognosis in posttreatment assessment. Results underscore the necessity of including psychological symptom improvement, as well as consistency across research and practice, in defining remission in adolescent BN.

Indexed as

AdolescentBulimia NervosaEmpirical ResearchFemaleFollow-Up StudiesHumansMaleModels, TheoreticalTreatment Outcomeadolescentsbulimia nervosaeating disordersremission

Identifiers

PMID32130757
PMCPMC7311246
OpenAlexW3009731760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.