ArticlePlant molecular biology2020
AtDRO1 is nuclear localized in root tips under native conditions and impacts auxin localization.
Article in Plant molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 36 citations in OpenAlex.
- Root system architecture and drought adaptation: emerging tools and genetic insights.Frontiers in plant science · 2026Review
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- Root Meristem Maintenance Mechanisms are Key to Plant Defense Against Nanoplastics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Cellular and physiological functions of SGR family in gravitropic response in higher plants.Journal of advanced research · 2025Review
- PEG treatment is unsuitable to study root related traits as it alters root anatomy in barley (Hordeum vulgare L.).BMC plant biology · 2024Article
- Do DEEPER ROOTING 1 Homologs Regulate the Lateral Root Slope Angle in Cucumber (International journal of molecular sciences · 2024Article
- IGT/LAZY genes are differentially influenced by light and required for light-induced change to organ angle.BMC biology · 2024Article
- Durum wheat (Frontiers in plant science · 2024Article
- Article
- Editorial: Mechanisms of abiotic stress responses and tolerance in plants: physiological, biochemical and molecular interventions, volume II.Frontiers in plant science · 2023Article
- Gravity sensing and responses in the coordination of the shoot gravitropic setpoint angle.The New phytologist · 2022Review
- Leveraging orthology within maize and Arabidopsis QTL to identify genes affecting natural variation in gravitropism.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Crop Root Responses to Drought Stress: Molecular Mechanisms, Nutrient Regulations, and Interactions with Microorganisms in the Rhizosphere.International journal of molecular sciences · 2022Review
- Expression of PotatoFrontiers in plant science · 2022Article
- Root plasticity under abiotic stress.Plant physiology · 2021Review
- A single-cell view of the transcriptome during lateral root initiation in Arabidopsis thaliana.The Plant cell · 2021Article
- Wheat root systems as a breeding target for climate resilience.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Understanding the Intricate Web of Phytohormone Signalling in Modulating Root System Architecture.International journal of molecular sciences · 2021Review
- Pulse Root Ideotype for Water Stress in Temperate Cropping System.Plants (Basel, Switzerland) · 2021Review
- Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
DEEPER ROOTING 1 (DRO1) contributes to the downward gravitropic growth trajectory of roots upstream of lateral auxin transport in monocots and dicots. Loss of DRO1 function leads to horizontally oriented lateral roots and altered gravitropic set point angle, while loss of all three DRO family members results in upward, vertical root growth. Here, we attempt to dissect the roles of AtDRO1 by analyzing expression, protein localization, auxin gradient formation, and auxin responsiveness in the atdro1 mutant. Current evidence suggests AtDRO1 is predominantly a membrane-localized protein. Here we show that VENUS-tagged AtDRO1 driven by the native AtDRO1 promoter complemented an atdro1 Arabidopsis mutant and the protein was localized in root tips and detectable in nuclei. atdro1 primary and lateral roots showed impairment in establishing an auxin gradient upon gravistimulation as visualized with DII-VENUS, a sensor for auxin signaling and proxy for relative auxin distribution. Additionally, PIN3 domain localization was not significantly altered upon gravistimulation in atdro1 primary and lateral roots. RNA-sequencing revealed differential expression of known root development-related genes in atdro1 mutants. atdro1 lateral roots were able to respond to exogenous auxin and AtDRO1 gene expression levels in root tips were unaffected by the addition of auxin. Collectively, the data suggest that nuclear localization may be important for AtDRO1 function and suggests a more nuanced role for DRO1 in regulating auxin-mediated changes in lateral branch angle. KEY MESSAGE: DEEPER ROOTING 1 (DRO1) when expressed from its native promoter is predominately localized in Arabidopsis root tips, detectable in nuclei, and impacts auxin gradient formation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.