Evidence map›Paper›PMID 32130579›Full record

Observational studyClinical rheumatology2020

Prevalence of Sjögren's syndrome associated with rheumatoid arthritis in the USA: an observational study from the Corrona registry.

Leslie R Harrold, Ying Shan, Sabrina Rebello, Neil Kramer, Sean E Connolly, Evo Alemao, Sheila Kelly, Joel M Kremer, Elliot D Rosenstein

Open access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Epidemiology of Sjögren syndrome.Nature reviews. Rheumatology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. [Clinical characteristics and risk factors of rheumatoid arthritis with ulcerative keratitis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Leslie R HarroldCorrona, LLC, 1440 Main Street, Suite 310, Waltham, MA, 02451, USA. lharrold@corrona.org.ORCID https://orcid.org/0000-0002-0170-2747
Ying ShanCorrona, LLC, 1440 Main Street, Suite 310, Waltham, MA, 02451, USA.
Sabrina RebelloCorrona, LLC, 1440 Main Street, Suite 310, Waltham, MA, 02451, USA.ORCID https://orcid.org/0000-0002-0201-4030
Neil KramerInstitute for Rheumatic & Autoimmune Diseases, Overlook Medical Center, Summit, NJ, USA.
Sean E ConnollyBristol-Myers Squibb, Princeton, NJ, USA.
Evo AlemaoBristol-Myers Squibb, Princeton, NJ, USA.
Sheila KellyBristol-Myers Squibb, Princeton, NJ, USA.
Joel M KremerAlbany Medical College and the Center for Rheumatology, Albany, NY, USA.
Elliot D RosensteinInstitute for Rheumatic & Autoimmune Diseases, Overlook Medical Center, Summit, NJ, USA.ORCID https://orcid.org/0000-0001-7681-4615
Bristol-Myers Squibb (United States) · USOverlook Medical Center · USCenter for Rheumatology · USUniversity of Massachusetts Chan Medical School · US

Funding

Bristol-Myers Squibb N/A
6 · The paper itself

Abstract

The objectives of this analysis were to assess the prevalence of Sjögren's syndrome (SS) associated with rheumatoid arthritis (RA) and to compare baseline characteristics of patients with RA with and without SS. Adult patients with RA from a large observational US registry (Corrona RA), with ≥ 1 visit for assessment of SS status between 22 April 2010 and 28 February 2018, were considered. Patients with RA with versus without SS were compared. SS status was determined from a yes/no variable and reported at enrollment into the Corrona RA registry and follow-up visits. Outcomes were unadjusted prevalence of SS in patients with RA, prevalence of SS by RA disease duration, and baseline characteristics in patients with RA by SS status. Of 24,528 eligible patients, 7870 (32.1%) had a diagnosis of RA and SS. The unadjusted overall rate for SS prevalence in patients with RA was 0.30 (95% confidence interval 0.29, 0.31). SS prevalence increased with increasing RA duration. Patients with RA with versus without SS were more likely to be older, female, and seropositive; had a longer RA duration; higher disease activity; and a higher incidence of comorbidities (hypertension, cardiovascular disease, malignancies, and serious infections), erosive disease, and subcutaneous nodules at index date. Patients with RA and SS had a higher disease burden than those with RA only. The prevalence of SS increased as duration of RA increased. RA with SS was associated with seropositivity, more severe RA, extra-articular manifestations, and comorbidities.Key Points• The overall prevalence of SS among patients with RA was 30%.• The prevalence of SS increased with increasing RA disease duration.• Identifying specific clinical characteristics of patients with RA with SS, such as a greater incidence of extra-articular manifestations and comorbidities, may help clinicians to better characterize this patient population.

Indexed as

AgedArthritis, RheumatoidFemaleHealth StatusHumansMaleMiddle AgedPrevalenceProspective StudiesRegistriesSjogren's SyndromeUnited StatesObservational studyPrevalenceRheumatoid arthritisSjögren’s syndrome

Identifiers

PMID32130579
PMCPMC7237400
OpenAlexW3009565248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.