Evidence map›Paper›PMID 32130495›Full record

ArticleEuropean radiology2020

Feasibility of shear wave sonoelastography to detect endoleak and evaluate thrombus organization after endovascular repair of abdominal aortic aneurysm.

Nicolas Voizard, Antony Bertrand-Grenier, Husain Alturkistani, Eric Therasse, An Tang, Claude Kauffmann, Guy Cloutier, Gilles Soulez

Abstract read
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In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nicolas VoizardLaboratory of Clinical Imaging Processing, Centre hospitalier de l'Université de Montréal (CHUM) Research Center (CRCHUM), Montréal, Québec, Canada.
Antony Bertrand-GrenierLaboratory of Clinical Imaging Processing, Centre hospitalier de l'Université de Montréal (CHUM) Research Center (CRCHUM), Montréal, Québec, Canada.
Husain AlturkistaniLaboratory of Clinical Imaging Processing, Centre hospitalier de l'Université de Montréal (CHUM) Research Center (CRCHUM), Montréal, Québec, Canada.
Eric TherasseLaboratory of Clinical Imaging Processing, Centre hospitalier de l'Université de Montréal (CHUM) Research Center (CRCHUM), Montréal, Québec, Canada.
An TangLaboratory of Clinical Imaging Processing, Centre hospitalier de l'Université de Montréal (CHUM) Research Center (CRCHUM), Montréal, Québec, Canada.
Claude KauffmannLaboratory of Clinical Imaging Processing, Centre hospitalier de l'Université de Montréal (CHUM) Research Center (CRCHUM), Montréal, Québec, Canada.
Guy CloutierDepartment of Radiology, Centre hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada.
Gilles SoulezLaboratory of Clinical Imaging Processing, Centre hospitalier de l'Université de Montréal (CHUM) Research Center (CRCHUM), Montréal, Québec, Canada. gilles.soulez.chum@ssss.gouv.qc.ca.ORCID http://orcid.org/0000-0002-5566-3552
Centre Hospitalier de l’Université de Montréal · CAThe Quebec Population Health Research Network · CA

Funding

canadian institute of health research MOP #115099Fonds de Recherche du Québec - Santé 34939Fonds de Recherche du Québec - Santé ARQ #22951
6 · The paper itself

Abstract

purposeTo investigate the feasibility of shear wave sonoelastography (SWS) for endoleak detection and thrombus characterization of abdominal aortic aneurysm (AAA) after endovascular repair (EVAR). MATERIALS AND

methodsParticipants who underwent EVAR were prospectively recruited between November 2014 and March 2016 and followed until March 2019. Elasticity maps of AAA were computed using SWS and compared to computed tomography angiography (CTA) and color Doppler ultrasound (CDUS). Two readers, blinded to the CTA and CDUS results, reviewed elasticity maps and B-mode images to detect endoleaks. Three or more CTAs per participant were analyzed: pre-EVAR, baseline post-EVAR, and follow-ups. The primary endpoint was endoleak detection. Secondary endpoints included correlation between total thrombus elasticity, proportion of fresh thrombus, and aneurysm growth between baseline and reference CTAs. A 3-year follow-up was made to detect missed endoleaks, EVAR complication, and mortality. Data analyses included Cohen's kappa; sensitivity, specificity, and positive predictive value (PPV); Pearson coefficient; and Student's t tests.

resultsSeven endoleaks in 28 participants were detected by the two SWS readers (k = 0.858). Sensitivity of endoleak detection with SWS was 100%; specificity and PPV averaged 67% and 50%, respectively. CDUS sensitivity was estimated at 43%. Aneurysm growth was significantly greater in the endoleak group compared to sealed AAAs. No correlation between growth and thrombus elasticity or proportion of fresh thrombus in AAAs was found. No new endoleaks were observed in participants with SWS negative studies.

conclusionSWS has the potential to detect endoleaks in AAA after EVAR with comparable sensitivity to CTA and superior sensitivity to CDUS. KEY POINTS: • Dynamic elastography with shear wave sonoelastography (SWS) detected 100% of endoleaks in abdominal aortic aneurysm (AAA) follow-up that were identified by a combination of CT angiography (CTA) and color Doppler ultrasound (CDUS). • Based on elasticity maps, SWS differentiated endoleaks from thrombi within the aneurysm sac (p < 0.001). • After 3-year follow-up, no new endoleaks were observed in SWS negative examinations.

Indexed as

AgedAged, 80 and overAortic Aneurysm, AbdominalComputed Tomography AngiographyElasticity Imaging TechniquesEndoleakEndovascular ProceduresFeasibility StudiesFemaleFollow-Up StudiesHumansMaleProspective StudiesSensitivity and SpecificityThrombosisUltrasonography, Doppler, ColorAbdominal aortic aneurysmColor Doppler ultrasoundCT angiographyElastographyEndoleak

Identifiers

PMID32130495
OpenAlexW3010047384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.